Recruiting

Broccoli Microgreen Metabotyping in Obese Breast Cancer Survivors

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Study Aim

This study examines the feasibility and compliance of consuming broccoli microgreens in obese breast cancer survivor women, with the goal of assessing its impact on their health over a two-week period.

What is being tested

Broccoli microgreen (BMG)

Other
Who is being recruted

Body Weight+11

+ Breast Diseases

+ Breast Neoplasms

+9 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Supportive Care Study

Interventional
Study Start: December 2025
See protocol details

Summary

Principal SponsorUniversity of Maryland, Baltimore
Study ContactYuanyuan (Rose) Li, M.D., Ph.D.
Last updated: December 24, 2025
Sourced from a government-validated database.Claim as a partner

Study start date: December 3, 2025

Actual date on which the first participant was enrolled.

This clinical trial is focused on exploring the potential health benefits of broccoli microgreens for obese breast cancer survivors. The study involves participants from the University of Maryland Medical Center in Baltimore who will incorporate a specific serving of raw broccoli microgreens into their daily meals for two weeks. The researchers aim to determine if this addition is practical for the participants and whether it can positively affect their metabolism and gut health. The insights gained from this study could lead to new strategies to improve the management of obesity and metabolic disorders in breast cancer survivors, complementing traditional care and supporting long-term health. Participants in the study will consume broccoli microgreens as part of their regular diet and undergo assessments to track changes in their metabolic parameters and gut health. To measure the effects, the study will collect biological samples such as blood and fecal samples, and participants will also complete questionnaires at the beginning and end of the two-week period. This information will help evaluate the feasibility of the intervention and any potential health benefits, providing valuable data on how broccoli microgreens might assist in managing obesity-related issues for breast cancer survivors.

Official TitleMetabotyping of a Functional Food, Broccoli Microgreen, in Obese Breast Cancer Survivors 
NCT07032545
Principal SponsorUniversity of Maryland, Baltimore
Study ContactYuanyuan (Rose) Li, M.D., Ph.D.
Last updated: December 24, 2025
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

24 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Supportive Care Study

These studies explore ways to improve comfort and daily life for people living with a condition. They may focus on easing symptoms, reducing treatment side effects, or supporting overall well-being.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Female

Biological sex of participants that are eligible to enroll.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Body WeightBreast DiseasesBreast NeoplasmsNeoplasmsNeoplasms by SiteNutrition DisordersNutritional and Metabolic DiseasesObesitySigns and SymptomsSkin DiseasesPathological Conditions, Signs and SymptomsSkin and Connective Tissue DiseasesOvernutritionOverweight

Criteria

6 inclusion criteria required to participate
Female

Had a diagnosis of breast cancer (Stage I-III)

2 to 60 months post-curative treatment (surgery, chemotherapy, and/or radiation)

BMI > 30 kg/m² (obese classification)

Show More Criteria

3 exclusion criteria prevent from participating
Have any contraindications to the proposed nutrition intervention as identified by their medical provider, their designee, or the study team (e.g., GI conditions, medication requirements, pregnancy, breastfeeding, recent history of an eating disorder).

Allergy or intolerance to cruciferous vegetables

Currently taking broccoli extract supplements

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
All participants are in BMG group and will consume one serving size (one cup, \~57 gram) of raw BMG daily for 2-week period of time.

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

Breast Evaluation and Treatment Program, University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center

Baltimore, United StatesSee the location
Recruiting
One Study Center