Completed

VegAnimalPlant-Based Meat Analogues' Impact on Human Health Study

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Study Aim

This study examines how consuming plant-based meat analogues affects plasma glucose, insulin, leptin, and ghrelin levels at various times after eating.

What is being tested

Postprandial Vegan Meat

+ Postprandial Meat

Other
Who is being recruted

Hyperinsulinism+2

+ Insulin Resistance

+ Metabolic Diseases

From 25 to 50 Years
+10 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Prevention Study

Interventional
Study Start: February 2022
See protocol details

Summary

Principal SponsorUniversidad de Extremadura
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: February 6, 2022

Actual date on which the first participant was enrolled.

This study explores how eating plant-based meat alternatives compares to eating traditional beef in terms of how full people feel afterward. It involves 25 healthy adults, both men and women aged 25 to 50. The study is important because understanding how these alternative meats affect fullness and subsequent eating can help guide healthier eating habits. This knowledge is especially relevant as more people are choosing plant-based diets for health and environmental reasons. Participants in the study eat either vegan "meat" or beef after fasting for 12 hours. Their blood is collected before and after eating to measure levels of certain hormones and nutrients. They are asked to stay seated and do mild activities like reading, to avoid affecting digestion. After two hours, participants can eat spaghetti freely to see how much they eat after feeling full from the initial meal. The study uses a crossover design, meaning participants switch foods after a two-week break, ensuring the comparisons are accurate. This design helps better understand the differences in how these foods might affect appetite and overall caloric intake.

Official TitleImpact of Plant-Based Meat Analogues Consumption on Human Health
NCT07031752
Principal SponsorUniversidad de Extremadura
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

25 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Prevention Study

Prevention studies aim to stop a disease from developing. They often involve people at risk and test things like vaccines, lifestyle changes, or preventive medications.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 25 to 50 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

HyperinsulinismInsulin ResistanceMetabolic DiseasesNutritional and Metabolic DiseasesGlucose Metabolism Disorders

Criteria

5 inclusion criteria required to participate
Body mass index (BMI) between 18-25 kg/m2.

No clinical signs of metabolic disease (HbA1c < 5.7%).

Normotensive (<95th centile for height, sex and age).

Lipid profiles and liver enzymes (aspartate transaminase (AST) and alanine transaminase (ALT)) within physiological range.

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5 exclusion criteria prevent from participating
Smoking.

Drinking alcohol.

Food allergies.

Dietary restrictions.

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Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
In the first stage, participants were randomly allocated to eat whether vegan meat (VM) or genuine meat (GM) along with water (100 cL).

Group II

Experimental
The second stage, conducted after a minimum washout period of two weeks following the first stage, was conducted following the same procedure as described for the first stage. Yet, participants shifted positions in relation to the first meal.

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

University of Extremadura

Cáceres, SpainOpen University of Extremadura in Google Maps
CompletedOne Study Center