Recruiting

Therapeutic Semiconductor Socks for Ankle Injury Recovery

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What is being tested

Semiconductor Embedded Sock

+ Control Compression Sock

Device
Who is being recruted

Leg Injuries+1

+ Sprains and Strains

+ Wounds and Injuries

From 18 to 70 Years
See all eligibility criteria
How is the trial designed

Treatment Study

Placebo-Controlled
Interventional
Study Start: April 2025
See protocol details

Summary

Principal SponsorUniversity of Colorado, Denver
Study ContactStudy Coordinator
Last updated: December 11, 2025
Sourced from a government-validated database.Claim as a partner

Study start date: April 10, 2025

Actual date on which the first participant was enrolled.

Ankle injuries, such as sprains and fractures, are common and often occur due to the complex structure and frequent use of the foot and ankle. This study is important because it explores a new treatment option using special therapeutic socks to help people recover from non-surgical ankle injuries. These socks are embedded with semiconductors that can help increase blood circulation, reduce inflammation and pain, and enhance the healing process. The goal is to see if these socks can improve rehabilitation outcomes, reduce the recurrence of injuries, and help people return to their normal activities more effectively. Participants in this study will wear the semiconductor embedded therapeutic socks for 12 weeks as part of their rehabilitation process for ankle injuries. The socks work by using the body's heat to release infrared waves and negative ions, which are believed to improve blood flow and reduce inflammation and pain. Researchers will evaluate the effectiveness of the socks by checking how well participants recover and monitoring their symptoms and ankle function over a period of up to a year. The study aims to provide both subjective feedback from participants and objective measures of improvement to determine if these specialized socks offer a beneficial new approach to ankle injury rehabilitation.

Official TitleClinical Outcomes Related to Treatment of Ankle Injury Using Semiconductor Embedded Therapeutic Socks: A Randomized, Prospective, Double Blinded Clinical Study 
Principal SponsorUniversity of Colorado, Denver
Study ContactStudy Coordinator
Last updated: December 11, 2025
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

100 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 70 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Leg InjuriesSprains and StrainsWounds and InjuriesAnkle Injuries

Criteria

Inclusion Criteria: * Ankle sprain, avulsion fracture, distal fibular fracture * Pain for at least 1 day * Patients 18-69 years old Exclusion Criteria: * Patients with neurological conditions * Patients with prior surgical treatment of lower limb injury * Patients with chronic pain conditions * Patient with auto-immune or auto-inflammatory disease * Patients with tobacco use in last 90 days * Patients with history of metabolic disorders * Patients with open wound at area of application * Patients with acute or systemic infection

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

50% chance of being blinded to the placebo group

Treatment Groups

Group I

Experimental

Group II

Placebo

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

University of Colorado

Aurora, United StatesSee the location
Recruiting
One Study Center