Recruiting

Digital Health Promotion Program for Older Adults with Cancer

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

Cancer, Older adults, Balance and Resistance Activities

Behavioral
Who is being recruted

Neoplasm Metastasis+1

+ Neoplasms

+ Neoplastic Processes

Over 65 Years
See all eligibility criteria
How is the trial designed

Supportive Care Study

Interventional
Study Start: May 2025
See protocol details

Summary

Principal SponsorMemorial Sloan Kettering Cancer Center
Study ContactKristen Fessele, PhD, RNMore contacts
Last updated: December 11, 2025
Sourced from a government-validated database.Claim as a partner

Study start date: May 30, 2025

Actual date on which the first participant was enrolled.

This study explores whether a digital health program called COBRA is a safe and practical option for older adults who have cancer. The focus is on using balance and resistance activities to help these individuals. The study aims to assess if such a program can be effectively used by this age group, providing an important step in improving supportive care and quality of life for older cancer patients. Participants in the study will engage in an 8-week digital health program specifically designed for them. The program will likely include activities that promote balance and resistance, which are crucial for maintaining strength and stability. Researchers will monitor the participants to evaluate the feasibility and safety of the program, ensuring it is a suitable option for older adults with cancer. While specific risks and benefits are not detailed, the study is crucial for understanding how to better support the health and well-being of this population.

Official TitleCOBRA: Cancer, Older Adults, Balance and Resistance Activities 
Principal SponsorMemorial Sloan Kettering Cancer Center
Study ContactKristen Fessele, PhD, RNMore contacts
Last updated: December 11, 2025
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

38 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Supportive Care Study

These studies explore ways to improve comfort and daily life for people living with a condition. They may focus on easing symptoms, reducing treatment side effects, or supporting overall well-being.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 65 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Neoplasm MetastasisNeoplasmsNeoplastic ProcessesPathologic Processes

Criteria

Inclusion Criteria: Older Adult Patients with Cancer - Are within 1 year of completion of primary therapy for cancer OR have a diagnosis of metastatic cancer; 1. For the purpose of this study, primary therapy is defined as treatment of curative intent, first-line or later, from which the individual is advancing to active surveillance or follow-up with or without maintenance therapy. 2. Individuals with metastatic cancer may be included provided they have stable disease or better per most recent restaging exam at time of enrollment. i. Patients with stable metastatic bony disease at most recent restaging exam and a score of 0-2 on the Functional Pain Scale (FPS69; Appendix 18) are eligible. The PI will consult with the Rehab Med co-PI for FPS scores of 3 or greater, by patient request or PI discretion. ii. Patients with symptomatic visceral metastases will be evaluated on a case-by-case basis at time of enrollment. * Are aged 65 years and older, with no upper age limit; * ECOG PS 0-3 or Karnofsky PS greater than or equal to 40; * Can read and speak English; * Self-report access to internet connection sufficient to support videoconferencing. Clinicians * Licensed clinician (MD, RN, APP) with an interest in the care of older adults with cancer. Exclusion Criteria: Older Adult Patients with Cancer * Have any cognitive impairment, neurologic, musculoskeletal, or other comorbid condition (as assessed by their provider) that would prevent the individual from engaging with the digital health coaching program or complete study assessments or engage in progressive intensity levels of physical activity * Have a neurologic, musculoskeletal, or other comorbid condition that would impede their ability to safely engage in progressive intensity levels of physical activity (as assessed by their provider). Patients with metastatic disease and suspected interim progression since last restaging exam will be referred back to their primary oncology care team for evaluation prior to enrollment. * Have activity restrictions post-surgery at the time of enrollment Clinicians No expected exclusions

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
Older Adult Patients with Cancer are within 1 year of completion of primary therapy for cancer OR have a diagnosis of metastatic cancer;

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 6 locations

Recruiting

Memorial Sloan Kettering Monmouth (Consent only)

Middletown, United StatesSee the location
Recruiting

Memorial Sloan Kettering Bergen (Consent Only)

Montvale, United States
Recruiting

Memorial Sloan Kettering Suffolk-Commack (Consent Only)

Commack, United States
Recruiting

Memorial Sloan Kettering Westchester (Consent only)

Harrison, United States
Recruiting
6 Study Centers