Pemvidutide for Alcohol-Associated Liver Disease
Pemvidutide
+ Placebo
Treatment Study
Summary
Study start date: June 16, 2025
Actual date on which the first participant was enrolled.This study is conducted to explore the effectiveness and safety of a drug called pemvidutide in treating people with alcohol-associated liver disease (ALD). ALD is a condition where the liver is damaged due to excessive alcohol consumption, and finding effective treatments is crucial for improving the health and lives of those affected. Participants in this study include individuals diagnosed with ALD, and the results could potentially offer a new treatment option for managing this disease. Participants in this trial receive an injection of either pemvidutide or a placebo (an inactive substance) once a week. The study is designed to ensure that neither the participants nor the researchers know who receives the actual medication or the placebo, a method called double-blind, to prevent bias. The main goal is to assess how well pemvidutide works in treating ALD and to ensure it is safe for use. By comparing the results from both groups, researchers aim to determine the efficacy and safety of the treatment.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.100 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.From 18 to 75 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.2 intervention groups are designated in this study
50% chance of being blinded to the placebo group
Treatment Groups
Group I
ExperimentalGroup II
PlaceboStudy Objectives
Primary Objectives
Secondary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 43 locations
Altimmune Clinical Study Site
North Little Rock, United StatesOpen Altimmune Clinical Study Site in Google MapsAltimmune Clinical Study Site
Doral, United StatesAltimmune Clinical Study Site
Miami, United StatesAltimmune Clinical Study Site
St Louis, United States