Recruiting

AI Assisted Legacy Program for Serious Illness Patients

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What is being tested

AI Assisted Personalized Legacy Program

Behavioral
Who is being recruted

Over 18 Years
See all eligibility criteria
How is the trial designed

Supportive Care Study

Interventional
Study Start: August 2025
See protocol details

Summary

Principal SponsorMayo Clinic
Study ContactMelissa FeltMore contacts
Last updated: December 11, 2025
Sourced from a government-validated database.Claim as a partner

Study start date: August 11, 2025

Actual date on which the first participant was enrolled.

This study is exploring a new kind of therapy program for people dealing with serious illnesses. The program uses artificial intelligence to help create a "legacy" document, which is a personal reflection of the patient's life. The goal is to help ease emotional distress and provide comfort by allowing patients to think about and share their life stories with loved ones. This can be especially important for patients who want to leave something meaningful for their family and friends. The study is being conducted at several locations under the Mayo Clinic and is considered to be low risk for participants. Participants in the study will work with a trained facilitator to talk about their life experiences and memories. These conversations are recorded and turned into a written document. The facilitator helps the patient review and edit the document to ensure it accurately reflects their thoughts and feelings. The final "legacy" document is then given to the patient to keep and share with their loved ones. This process is designed to be safe and supportive, providing emotional benefits to the participants by helping them create a tangible legacy.

Official TitleFeasibility and Acceptability of AI Assisted Personalized Legacy Program (Reflections: My Story) for Patients With Serious Illness 
NCT07009210
Principal SponsorMayo Clinic
Study ContactMelissa FeltMore contacts
Last updated: December 11, 2025
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

40 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Supportive Care Study

These studies explore ways to improve comfort and daily life for people living with a condition. They may focus on easing symptoms, reducing treatment side effects, or supporting overall well-being.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Criteria

Participant population: Adults with serious illness - defined as a health condition that carries a high risk of mortality Inclusion Criteria for patients: 1. Age ≥18 years 2. English fluency 3. Provide informed consent 4. Ability to complete questionnaire(s) by themselves or with assistance Exclusion Criteria: 1. Other psychological co-morbidities such as untreated schizophrenia, bipolar disease 2. Recent suicide attempt or psychiatric illness severe enough that hospitalization has been necessary in last 6 months 3. Active delirium 4. Advanced dementia 5. Participation in concurrent legacy offerings through the palliative care clinic

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 2 locations

Recruiting

Mayo Clinic

Phoenix, United StatesSee the location
Recruiting

Mayo Clinic

Rochester, United States
Recruiting
2 Study Centers