Recruiting soon

MRI vs. Transvaginal Ultrasound in Deep Infiltrating Endometriosis Diagnosis

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being collected

Data Collection

Collected from past medical records and data - Retrospective
Who is being recruted

Over 18 Years
+6 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Cohort

Tracking disease incidence in order to identify risk factors and understand disease progression over time.
Observational
Study Start: June 2025
See protocol details

Summary

Principal SponsorZiekenhuis Oost-Limburg
Study ContactPerrine de WalqueMore contacts
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: June 1, 2025

Actual date on which the first participant was enrolled.

This study focuses on improving the diagnosis and surgical planning for women with deep infiltrating endometriosis (DIE), a condition where tissue similar to the lining inside the uterus grows outside it, causing pain and fertility issues. Women of reproductive age are the primary group affected by this condition. Traditionally, diagnosing endometriosis takes several years, partly due to the invasiveness of the gold-standard diagnostic method, laparoscopy. However, non-invasive imaging techniques such as transvaginal ultrasound (TVS) and magnetic resonance imaging (MRI) have shown promise in reducing this delay. This study specifically aims to evaluate how well TVS performs in detecting DIE before surgery and examines whether adding MRI could improve surgical planning. Participants in this study undergo TVS to assess the presence of DIE, with findings being compared to actual surgical observations to measure the accuracy of this imaging technique. The study evaluates how well TVS identifies the location and extent of endometriosis lesions using the #ENZIAN classification system. Additionally, the study investigates if including MRI alongside TVS provides better insights for preoperative planning, especially in complex cases requiring coordination between different surgical specialists. The goal is to determine the best approach to ensure effective treatment and management, ultimately enhancing patient care and outcomes.

Official TitleThe Added Value of (Standard) Magnetic Resonance Imaging Compared to Transvaginal Ultrasound for the Preoperative Planning and Diagnosis of Deep Infiltrating Endometriosis: a Multicenter Retrospective Study.
NCT06994091
Principal SponsorZiekenhuis Oost-Limburg
Study ContactPerrine de WalqueMore contacts
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

200 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Cohort

These studies follow a group of individuals with common characteristics (such as a condition or birth year) over a specific period to study health outcomes or exposures.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Criteria

Female

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Criteria

1 inclusion criteria required to participate
All patients who underwent preoperative imaging at AZ Sint-Jan AV and Ziekenhuis Oost-Limburg (ZOL) between October 2021 and December 2024, TVS with or without complementary MR followed by therapeutic surgery as part of DIE.

5 exclusion criteria prevent from participating
Performing imaging, TVS with or without additional MR, by an operator without specific experience in the field.

Lack of a TVS report diagnosing DIE.

Preoperative diagnosis of only superficial endometriosis and/or endometriomas without DIE.

Performance of surgery by a surgeon without specific experience in the field.

Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Ziekenhuis Oost-Limburg

Genk, BelgiumOpen Ziekenhuis Oost-Limburg in Google Maps
Recruiting soonOne Study Center