Completed

Upper-extremity Plyometrics for Muscle Strength in Children With Hemiparetic Cerebral Palsy

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What is being tested

Plyometric Exercise

+ Standard exercise program

Other
Who is being recruted

Brain Damage, Chronic+2

+ Brain Diseases

+ Central Nervous System Diseases

From 10 to 15 Years
+9 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Interventional
Study Start: February 2023
See protocol details

Summary

Principal SponsorCairo University
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: February 12, 2023

Actual date on which the first participant was enrolled.

This study focuses on improving muscle strength and movement abilities in children with hemiparetic cerebral palsy, a condition that affects movement on one side of the body. It involves children aged 10 to 15 years who have mild to moderate movement challenges and are receiving treatment at a university clinic and hospitals in Saudi Arabia. The aim is to determine if a specific exercise program, called Plyo-Ex, can enhance their strength and functionality better than the usual exercises they are given. This research is important because it could lead to more effective therapies that help children with this condition improve their physical abilities and overall quality of life. In this study, participants are divided into two groups. One group follows the Plyo-Ex training program, which includes exercises like push-ups and ball activities, twice a week for 12 weeks, with each session lasting 45 minutes. The other group follows a standard exercise routine. The effectiveness of these programs is evaluated by measuring muscle strength through specific devices and assessing hand function using recognized performance tests. By comparing the outcomes between the two groups, researchers aim to identify which program is more beneficial. The study ensures all activities are safe and adhere to established guidelines, minimizing any potential risks for the participants.

Official TitleClinical Utility of Upper-extremity Plyometrics for Enhancing Muscle Strength and Functional Capabilities in Children With Hemiparetic Cerebral Palsy: a Randomized Controlled Trial
NCT06980246
Principal SponsorCairo University
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

58 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 10 to 15 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Brain Damage, ChronicBrain DiseasesCentral Nervous System DiseasesCerebral PalsyNervous System Diseases

Criteria

4 inclusion criteria required to participate
Unilateral cerebral palsy

Age 10-15 years

Motor function level I or II according to the Gross Motor Function Classification System.

Spasticity level 1 or 1+ according to the Modified Ashworth Scale

5 exclusion criteria prevent from participating
Structural deformities/contractures

Musculoskeletal or neural surgery in the last year

BOTOX injection in the last 6 months.

Cardiopulmonary disorders that could be exacerbated by exercise.

Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
Children in this group received the Plyo-Ex program

Group II

Active Comparator
Children in this group received the standard exercise program.

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Ragab K. Elnaggar

Al Kharj, Saudi ArabiaOpen Ragab K. Elnaggar in Google Maps
CompletedOne Study Center