Subgingival Instrumentation Effects on Stress Load in Periodontitis Patients
Sub-gingival instrumentation
Chronic Disease+7
+ Inflammation
+ Stomatognathic Diseases
Treatment Study
Summary
Study start date: June 10, 2025
Actual date on which the first participant was enrolled.This study investigates how subgingival instrumentation, a common dental procedure, affects the overall stress burden, known as allostatic load, in individuals with periodontitis, a severe gum disease. Stress is linked to many chronic health problems, and its effects can disrupt the body's normal functioning, leading to conditions like high blood pressure and diabetes. In the mouth, stress can worsen gum diseases by affecting the immune system and encouraging harmful habits like smoking or neglecting oral hygiene. This research is important because it seeks to clarify how stress impacts gum disease and overall health, potentially leading to better care for people with periodontitis by addressing the role of stress and improving both oral and general health outcomes. Participants in the study will undergo subgingival instrumentation, which involves cleaning below the gum line to remove plaque and tartar. This procedure will help researchers measure changes in stress-related biomarkers, such as cortisol levels and other indicators of bodily stress responses. The study aims to understand whether this dental treatment can influence the body's stress markers and improve gum health. By examining these effects, the study hopes to provide insights into the relationship between stress, oral health, and systemic health, potentially revealing new ways to manage periodontitis and reduce its long-term impacts on health.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.112 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.From 30 to 50 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.One single intervention group is designated in this study
This study does not include a placebo group
Treatment Groups
Group I
ExperimentalStudy Objectives
Primary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location