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Physical Activity Levels in Adolescents with Familial Mediterranean Fever

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What is being collected

Data Collection

Collected at a single point in time - Cross-sectional
Who is being recruted

Behavior+3

+ Motor Activity

+ Congenital, Hereditary, and Neonatal Diseases and Abnormalities

From 12 to 18 Years
See all eligibility criteria
How is the trial designed

Cohort

Tracking disease incidence in order to identify risk factors and understand disease progression over time.
Observational
Study Start: May 2025
See protocol details

Summary

Principal SponsorIstanbul University - Cerrahpasa
Study ContactNilay Arman, PhDMore contacts
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: May 15, 2025

Actual date on which the first participant was enrolled.

Familial Mediterranean Fever (FMF) is a common rheumatic disease in children that can cause joint pain, muscle weakness, and fatigue, leading to lower levels of physical fitness. These symptoms often make it difficult for children with FMF to participate in physical activities, which is crucial for maintaining health. This study focuses on comparing the physical activity levels of adolescents with FMF to those of their healthy peers. Understanding these activity levels is important because it can help develop exercise programs that improve the quality of life and long-term health outcomes for these children. The results might also help shape future research and exercise guidelines for other chronic conditions in children. The study involves assessing physical activity in adolescents using the Adolescent Physical Activity Questionnaire (PAQ-A), a tool designed to measure activity over the past week. Participants answer questions about the frequency and type of physical activities they engaged in, with scores calculated to reflect overall activity levels. This study does not involve any treatments or interventions, focusing instead on observation and data collection. By understanding how active adolescents with FMF are, researchers aim to provide insights that could lead to better exercise recommendations and health strategies for managing FMF and similar chronic conditions in young people.

Official TitleInvestigation of Physical Activity in Adolescents Diagnosed With Familial Mediterranean Fever
Principal SponsorIstanbul University - Cerrahpasa
Study ContactNilay Arman, PhDMore contacts
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

172 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Cohort

These studies follow a group of individuals with common characteristics (such as a condition or birth year) over a specific period to study health outcomes or exposures.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 12 to 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

BehaviorMotor ActivityCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesFamilial Mediterranean FeverGenetic Diseases, InbornHereditary Autoinflammatory Diseases

Criteria

Inclusion criteria for patients with FMF: * Be between 12-18 years of age * Have been diagnosed with FMF for at least 6 months at the Pediatric Rheumatology Department of Istanbul Faculty of Medicine * Be undergoing routine medical treatment for FMF * Be willing to participate in the study Exclusion criteria for patients with FMF: * Adolescents whose participation in the study is not wanted by their family * Having vestibular or neurological balance problems * Presence of scoliosis, leg length discrepancy, or recent lower extremity surgery * Adolescents with visual or hearing impairments Inclusion criteria for healthy peers: * Be between 12-18 years of age * Be willing to participate in the study Exclusion criteria for healthy peers: * Adolescents whose participation in the study is not wanted by their family * Having vestibular or neurological balance problems * Presence of scoliosis, leg length discrepancy, or recent lower extremity surgery * Adolescents with visual or hearing impairments Exclusion criteria for removal: \- Leaving at least 3 questions unanswered in the questionnaires

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Istanbul University-Cerrahpasa

Istanbul, Turkey (Türkiye)Open Istanbul University-Cerrahpasa in Google Maps
Recruiting soonOne Study Center