Intracoronary Tirofiban for No-Reflow in STEMI Patients
Intracoronary tirofiban
+ Saline 0.9%
ST Elevation Myocardial Infarction+8
+ Cardiovascular Diseases
+ Heart Diseases
Treatment Study
Summary
Study start date: May 12, 2025
Actual date on which the first participant was enrolled.This clinical study focuses on patients experiencing a heart attack known as ST-segment-elevation myocardial infarction (STEMI). This condition often occurs when a plaque in the artery ruptures, obstructing blood flow to the heart. To restore this blood flow, a procedure called primary percutaneous coronary intervention (PCI) is typically used. However, a common issue called the "no-reflow" phenomenon can occur, leading to further complications. This study investigates whether using a drug called intracoronary tirofiban right after opening the blocked artery can help reduce the risk of no-reflow, potentially improving outcomes for patients. Participants in this study undergo the PCI procedure to address the blockage in their coronary artery. After the artery is opened, they receive the drug tirofiban directly into the coronary artery. The study aims to evaluate the effectiveness of this approach by observing if it reduces the occurrence of no-reflow. Although the study does not specify exact benefits or risks, the goal is to determine if this treatment strategy can lead to better recovery and fewer complications following a heart attack.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.60 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.Over 18 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.2 intervention groups are designated in this study
50% chance of being blinded to the placebo group
Treatment Groups
Group I
ExperimentalGroup II
PlaceboStudy Objectives
Primary Objectives
Secondary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location