Enrolling by invitation

AI System for Predicting Lymph Node Metastasis in Gastric Cancer

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What is being collected

Data Collection

Collected from today forward - Prospective
Who is being recruted

Lymphatic Metastasis+3

+ Neoplasm Metastasis

+ Neoplasms

From 18 to 80 Years
See all eligibility criteria
How is the trial designed

Cohort

Tracking disease incidence in order to identify risk factors and understand disease progression over time.
Observational
Study Start: January 2025
See protocol details

Summary

Principal SponsorQun Zhao
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: January 1, 2025

Actual date on which the first participant was enrolled.

This study focuses on creating and testing an artificial intelligence (AI) system designed to predict the spread of gastric cancer to the lymph nodes before surgery. By analyzing detailed images and pathology data from patients, this AI tool aims to determine not only if the cancer has spread, but also to pinpoint which specific lymph nodes are affected. This research targets people diagnosed with gastric cancer. The primary goal is to enhance the accuracy of current assessment methods, which can help doctors make more informed decisions about treatment options, potentially improving patient outcomes. In this observational study, participants undergo preoperative imaging and pathology tests. The AI system processes this data to predict lymph node involvement. After surgery, all lymph nodes are meticulously removed and examined to verify the AI's predictions. The study measures the AI model's accuracy in identifying lymph node metastasis, which is crucial for understanding its effectiveness in real-world clinical settings. This approach aims to provide a more precise diagnosis, which can be essential for tailoring personalized treatment plans.

Official TitleArtificial Intelligence-Based Prediction of Lymph Node Metastasis and Nodal Station Involvement in Gastric Cancer Using Preoperative Multimodal Imaging and Pathology Data
NCT06957678
Principal SponsorQun Zhao
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

1200 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Cohort

These studies follow a group of individuals with common characteristics (such as a condition or birth year) over a specific period to study health outcomes or exposures.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 80 Years

Range of ages for which participants are eligible to join.

Conditions

Pathology

Lymphatic MetastasisNeoplasm MetastasisNeoplasmsNeoplastic ProcessesPathologic ProcessesPathological Conditions, Signs and Symptoms

Criteria

Inclusion Criteria: * Age 18 years or older Histologically confirmed gastric adenocarcinoma Scheduled for curative-intent gastrectomy with lymphadenectomy Completed preoperative imaging with contrast-enhanced CT or MRI Available preoperative biopsy pathology report Able and willing to provide written informed consent Exclusion Criteria: * Evidence of distant metastasis on preoperative imaging Prior chemotherapy, radiotherapy, or major abdominal surgery Severe comorbidities contraindicating surgery Incomplete or poor-quality preoperative imaging or pathology data Pregnancy or lactation

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

the Fourth Hospital of Hebei Medical University

Shijiazhuang, ChinaOpen the Fourth Hospital of Hebei Medical University in Google Maps
Enrolling by invitationOne Study Center