AI System for Predicting Lymph Node Metastasis in Gastric Cancer
Data Collection
Collected from today forward - ProspectiveLymphatic Metastasis+3
+ Neoplasm Metastasis
+ Neoplasms
Cohort
Tracking disease incidence in order to identify risk factors and understand disease progression over time.Summary
Study start date: January 1, 2025
Actual date on which the first participant was enrolled.This study focuses on creating and testing an artificial intelligence (AI) system designed to predict the spread of gastric cancer to the lymph nodes before surgery. By analyzing detailed images and pathology data from patients, this AI tool aims to determine not only if the cancer has spread, but also to pinpoint which specific lymph nodes are affected. This research targets people diagnosed with gastric cancer. The primary goal is to enhance the accuracy of current assessment methods, which can help doctors make more informed decisions about treatment options, potentially improving patient outcomes. In this observational study, participants undergo preoperative imaging and pathology tests. The AI system processes this data to predict lymph node involvement. After surgery, all lymph nodes are meticulously removed and examined to verify the AI's predictions. The study measures the AI model's accuracy in identifying lymph node metastasis, which is crucial for understanding its effectiveness in real-world clinical settings. This approach aims to provide a more precise diagnosis, which can be essential for tailoring personalized treatment plans.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.1200 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Cohort
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.From 18 to 80 Years
Range of ages for which participants are eligible to join.Conditions
Pathology
Criteria
Inclusion Criteria: * Age 18 years or older Histologically confirmed gastric adenocarcinoma Scheduled for curative-intent gastrectomy with lymphadenectomy Completed preoperative imaging with contrast-enhanced CT or MRI Available preoperative biopsy pathology report Able and willing to provide written informed consent Exclusion Criteria: * Evidence of distant metastasis on preoperative imaging Prior chemotherapy, radiotherapy, or major abdominal surgery Severe comorbidities contraindicating surgery Incomplete or poor-quality preoperative imaging or pathology data Pregnancy or lactation
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.Study Objectives
Primary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
the Fourth Hospital of Hebei Medical University
Shijiazhuang, ChinaOpen the Fourth Hospital of Hebei Medical University in Google Maps