Completed

Cognitive and Physical Effects of Prediabetes and Type 2 Diabetes in Older Adults

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What is being collected

Data Collection

Collected at a single point in time - Cross-sectional
Who is being recruted

Diabetes Mellitus+7

+ Diabetes Mellitus, Type 2

+ Endocrine System Diseases

Over 60 Years
+15 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Case-Control

Comparing exposures between individuals with and without disease in order to identify potential risk factors.
Observational
Study Start: April 2025
See protocol details

Summary

Principal SponsorUşak University
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: April 15, 2025

Actual date on which the first participant was enrolled.

The study focuses on understanding how prediabetes and Type 2 Diabetes affect cognitive abilities, physical functioning, and levels of fatigue in older adults. Prediabetes is when blood sugar levels are higher than normal but not high enough to be classified as diabetes, and it can lead to Type 2 Diabetes. Both conditions are common among the elderly and can result in complications like memory problems, reduced physical strength, and chronic tiredness. These complications can lower the quality of life and increase the risk of issues like dementia and mobility difficulties. By understanding these effects, the study aims to improve management and care for older adults with these conditions. Participants in the study are divided into four groups: those with prediabetes, those with controlled and uncontrolled Type 2 Diabetes, and healthy older adults. The study will compare these groups to see differences in cognitive function, reaction times, sense of direction, ability to perform tasks simultaneously, physical abilities, and fatigue levels. To measure cognitive status, the Montreal Cognitive Assessment (MoCA) test is used, which evaluates mild cognitive impairments and early dementia. This test scores up to 30 points, with a score of 26 or higher considered normal. The study seeks to provide insights into how these conditions affect older adults, which could lead to better prevention and treatment strategies.

Official TitleEffects of Prediabetes and Type 2 Diabetes on Cognitive Status, Physical Function, and Fatigue in Geriatric Individuals: A Case-Control Study
NCT06953609
Principal SponsorUşak University
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

94 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Case-Control

These studies compare people who have a disease (cases) with those who don't (controls). The goal is to look back at previous exposures or risk factors to identify what might have contributed to the disease.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 60 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Diabetes MellitusDiabetes Mellitus, Type 2Endocrine System DiseasesFatigueMetabolic DiseasesNutritional and Metabolic DiseasesPrediabetic StateSigns and SymptomsPathological Conditions, Signs and SymptomsGlucose Metabolism Disorders

Criteria

5 inclusion criteria required to participate
for people without diabetes (healthy), those with Hemoglobin A1c Levels (HbA1c) normal range between 4% and 5.6%,

those with HbA1c level between 5.7% and 6.4%, those with prediabetes (Impaired Glucose Tolerance),

those with 6.5% -7.5% level and

those with HbA1c level above 7.5

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10 exclusion criteria prevent from participating
those who have major depression,

uncontrolled thyroid disease,

those with vitamin B12, folic acid deficiency and anemia,

those with uncontrolled hypertension,

Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Uşak Education and Research Hospital

Uşak, Turkey (Türkiye)Open Uşak Education and Research Hospital in Google Maps
CompletedOne Study Center
Cognitive and Physical Effects of Prediabetes and Type 2 Diabetes in Older Adults | PatLynk