Recruiting

Fluconazole vs. Itraconazole for Pityriasis Versicolor

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What is being tested

Fluconazole

+ Itraconazole

Drug
Who is being recruted

Bacterial Infections and Mycoses+5

+ Dermatomycoses

+ Infections

From 18 to 50 Years
+4 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Phase 4
Interventional
Study Start: March 2025
See protocol details

Summary

Principal SponsorKhyber Teaching Hospital
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: March 1, 2025

Actual date on which the first participant was enrolled.

Pityriasis versicolor is a skin condition caused by a fungus, leading to patches on the skin that can be lighter or darker than the surrounding areas. This study focuses on comparing two medications, fluconazole and itraconazole, which are both taken orally to treat this condition. The goal is to determine which medication is more effective in treating pityriasis versicolor. This is important as finding the more effective treatment could improve care for those suffering from this common skin infection. In this study, participants will receive either fluconazole or itraconazole orally. Researchers will observe the effects of these medications on the skin condition over time. The study does not specify particular outcomes being measured, but typically, effectiveness would be assessed by the improvement in skin appearance and reduction in fungal infection. Participants might experience side effects from the medications, as is common with oral antifungal treatments, but the study aims to identify which drug provides better results with the least issues.

Official TitleComparison of Efficacy of Oral Fluconazole Versus Oral Itraconazole in the Treatment of Pityriasis Versicolor
NCT06922344
Principal SponsorKhyber Teaching Hospital
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

106 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 50 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Bacterial Infections and MycosesDermatomycosesInfectionsMycosesSkin DiseasesSkin Diseases, InfectiousTinea VersicolorSkin and Connective Tissue Diseases

Criteria

1 inclusion criteria required to participate
All cases of Pityriasis versicolor

3 exclusion criteria prevent from participating
Patients with history of chronic renal or liver disease, malignancy , or undergoing any kind of chemotherapy or radiotherapy or having cardiac conduction abnormalities.

Patients who received any anti-fungal therapy in the last one month.

Pregnant or lactating women.

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
Group A consists of patients in whom oral fluconazole is given in dose of 300mg once weekly for 2 weeks.

Group II

Experimental
Group B consists of patients in whom oral Itraconazole is given in dose of 100mg Twice for 5 days.

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

Khyber Teaching Hospital

Peshawar, PakistanOpen Khyber Teaching Hospital in Google Maps
Recruiting
One Study Center