Recruiting

Nutrition Intervention for At-Risk Prediabetes Patients in Los Angeles

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What is being tested

One-arm feasibility pilot of a nutrition intervention to recruit, engage, and retain DPP participants in the safety-net setting in Los Angeles

Behavioral
Who is being recruted

Treatment Adherence and Compliance+7

+ Behavior

+ Diabetes Mellitus

From 18 to 99 Years
See all eligibility criteria
How is the trial designed

Prevention Study

Interventional
Study Start: December 2025
See protocol details

Summary

Principal SponsorCedars-Sinai Medical Center
Study ContactLeslie Aguilar-Hernandez, BA
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: December 8, 2025

Actual date on which the first participant was enrolled.

This study aims to explore how practical and well-received a new nutrition-focused approach is when added to the Diabetes Prevention Program (DPP) for individuals at risk of developing prediabetes. The goal is to see if hands-on cooking demonstrations can enhance the current DPP by helping participants better understand and apply nutrition concepts in their daily lives, potentially leading to weight loss and healthier eating habits. The study targets patients from community health centers in Los Angeles, focusing on those already engaged in DPP courses. This effort seeks to improve participation and retention in the program, providing a foundation for future research that could further refine diabetes prevention strategies. Participants in the study will join a 6-week educational program featuring cooking demonstrations led by trained community health workers and designed by registered dieticians. These sessions will be interactive, allowing participants to learn how to prepare healthy meals that help manage blood sugar levels. The classes will be held in person at a community resource center, with an option to join virtually. Throughout the six weeks, participants will have regular check-ins and complete surveys to assess their satisfaction, knowledge, and eating habits. The study will gather feedback and engagement data to evaluate how well this approach fits within the existing DPP framework and how acceptable it is to participants, aiming to guide future, larger-scale research efforts.

Official TitleOne-arm Feasibility and Acceptability Pilot Study of a Community-informed Nutrition Intervention to Recruit, Engage, and Retain Patients Who Are Eligible to Participate in the Diabetes Prevention Program at Two Community Health Centers in Los Angeles
NCT06897982
Principal SponsorCedars-Sinai Medical Center
Study ContactLeslie Aguilar-Hernandez, BA
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

20 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Prevention Study

Prevention studies aim to stop a disease from developing. They often involve people at risk and test things like vaccines, lifestyle changes, or preventive medications.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 99 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Treatment Adherence and ComplianceBehaviorDiabetes MellitusEndocrine System DiseasesMetabolic DiseasesNutritional and Metabolic DiseasesPatient Acceptance of Health CarePrediabetic StateHealth BehaviorGlucose Metabolism Disorders

Criteria

Inclusion Criteria: * 18+ years old * BMI of 25 or higher (23 or higher if Asian) * Meet specific blood sugar test criteria indicating prediabetes, such as a fasting plasma glucose level between 110-125 mg/dL or an A1C level between 5.7-6.4% * Not be diagnosed with type 1 or type 2 diabetes * Moderate to high risk of having prediabetes or a known diagnosis of prediabetes by their medical provider in the last 12 months. * Eligible or enrolled in the Diabetes Prevention Program Exclusion Criteria: * Younger than 18 years of age * BMI of less than 25 or higher (or under 23 if Asian) * Does not meet specific blood sugar test criteria indicating prediabetes, such as a fasting plasma glucose level between 110-125 mg/dL or an A1C level between 5.7-6.4% * Currently diagnosed with type 1 or type 2 diabetes * Has not been diagnosed as moderate to high risk of having prediabetes or having a known diagnosis of prediabetes by their medical provider in the last 12 months.

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
A single arm approach with two groups of ten collected a two different time points in the year of the clinic's DPP. These will not be compared to each other they will be used to collect feasibility outcomes data to inform a future pilot randomized study

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

Cedars-Sinai Medical Center

Los Angeles, United StatesOpen Cedars-Sinai Medical Center in Google Maps
Recruiting
One Study Center
Nutrition Intervention for At-Risk Prediabetes Patients in Los Angeles | PatLynk