Intracanal Corticosteroid Solution for Post-Endodontic Pain Relief in Irreversible Pulpitis and Apical Periodontitis

This study is focused on understanding if intentionally pushing a corticosteroid solution, specifically dexamethasone, beyond the root canal into the surrounding tissue can help reduce pain after root canal treatment. The study targets patients who have symptomatic irreversible pulpitis and symptomatic apical periodontitis, which are conditions associated with significant dental pain and inflammation. By exploring this method, the research aims to find better ways to manage pain without relying solely on traditional pain relief methods, potentially leading to improved recovery experiences for patients undergoing root canal procedures. Participants in this study will receive a root canal treatment where either a dexamethasone solution or a placebo is used. The method involves carefully allowing the solution to extend beyond the root canal into the tissues around the root. The main focus is to observe any reduction in pain levels following the procedure, comparing the effects of the corticosteroid to those of the placebo. This approach involves some degree of risk as it intentionally breaches the canal barrier, but it is closely monitored to ensure patient safety while investigating the potential benefits.