Suspended

Flapless Immediate Implant with Titanium Mesh vs Collagen Membrane for Anterior Teeth

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What is being tested

collagen membrane

+ titanium mesh

Procedure
Who is being recruted

From 21 to 50 Years
+10 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Interventional
Study Start: March 2025
See protocol details

Summary

Principal SponsorMisr International University
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: March 6, 2025

Actual date on which the first participant was enrolled.

This clinical trial aims to explore the effectiveness of two different methods for placing dental implants in patients who have issues with the bone in the front part of the mouth, especially where there is a deficiency in the buccal bone. The study involves patients who need implants due to roots or decayed teeth in the front area and have healthy overall conditions. One group will receive implants using a titanium mesh and a collagen membrane, while the other group will receive implants using only a collagen membrane. The goal is to determine which method better supports bone thickness and overall oral health, which can lead to improved outcomes in dental procedures. Participants in this study will undergo a procedure where implants are placed immediately after removing the damaged teeth without cutting the gum. For one group, the area will be treated with a xenograft and covered with a titanium mesh and collagen membrane, while the other group will use xenograft and collagen membrane only. The thickness of the bone and soft tissue will be measured at 6 and 12 months to evaluate success. Participants will also keep track of their pain and swelling for two weeks following the procedure. Follow-ups will ensure proper oral hygiene and medication will be provided as needed. The collected data will help identify the most effective method for implant placement.

Official TitleComparison of Flapless Immediate Implant Placement With Titanium Mesh Versus Immediate Implants Placement With Collagen Membrane in Type II Socket: A Randomized Clinical Trial
NCT06875830
Principal SponsorMisr International University
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

20 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.


Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 21 to 50 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Criteria

7 inclusion criteria required to participate
Patients who have at least one remaining root or badly decayed tooth in anterior maxilla.

Systemically free patients (American Society of Anesthesiologists I; ASA I)

Patients aged from 21 to 50 years old

Buccal bone partial deficiency (extraction socket type II)

Show More Criteria

3 exclusion criteria prevent from participating
Patients with habits that may jeopardize the implant longevity and affect the results of the study such as parafunctional habits such as bruxism

Smokers

Pregnant and lactating females

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Active Comparator
immediate implant placement will be done and augmentation of the buccal bone will be done with xenograft and collagen membrane

Group II

Active Comparator
immediate implant placement will be done and augmentation of the buccal bone will be done with xenograft and titanium mesh

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Faculty of oral & dental Medicine,Misr international University

Cairo, EgyptOpen Faculty of oral & dental Medicine,Misr international University in Google Maps
SuspendedOne Study Center