Recruiting

OGTT-CGMHome Glucose Tolerance Test Using Continuous Glucose Monitoring for Prediabetes

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What is being tested

OGTT at home using CGM

+ OGTT at the clinic

Diagnostic Test
Who is being recruted

Diabetes Mellitus+4

+ Endocrine System Diseases

+ Hyperglycemia

From 18 to 70 Years
+18 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Diagnostic Study

Interventional
Study Start: June 2025
See protocol details

Summary

Principal SponsorLinkoeping University
Study ContactPeder af Geijerstam, MD, PhD
Last updated: March 25, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: June 11, 2025

Actual date on which the first participant was enrolled.

This study examines an innovative way to perform an oral glucose tolerance test (OGTT) at home for people with prediabetes. It compares doing the test at home using a continuous glucose monitor (CGM) with the traditional method done in a clinic. By making testing more accessible and less burdensome, the study aims to see if this home method can provide results as reliable as the clinic tests. The goal is to see if home testing can help in early detection of issues with blood sugar levels, potentially leading to better management of prediabetes. Participants in the study will be split into two groups. One group will start with a clinic-based OGTT, while the other will begin with the home-based OGTT. Each participant will experience both methods. During the home test, a CGM will track glucose levels continuously, while the clinic test will use blood samples. The study will measure how closely the results from the home method match those from the clinic method, look at how glucose levels vary between the two tests, and evaluate how practical and comfortable home testing is for participants. This approach might offer a more convenient way to monitor glucose tolerance without frequent clinic visits.

Official TitleOral Glucose Tolerance Test at Home With Continuous Glucose Monitoring vs Standard Clinic-based Testing
NCT06862128
Principal SponsorLinkoeping University
Study ContactPeder af Geijerstam, MD, PhD
Last updated: March 25, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

75 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Diagnostic Study

Diagnostic studies focus on improving how we detect or confirm a disease. They test new tools or techniques that could provide faster or more accurate diagnoses.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 70 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Diabetes MellitusEndocrine System DiseasesHyperglycemiaMetabolic DiseasesNutritional and Metabolic DiseasesGlucose IntoleranceGlucose Metabolism Disorders

Criteria

6 inclusion criteria required to participate
Prediabetes indicated by >= 2 of the following values, measured at separate occasions or through different analyses during the past 2 years

Fasting venous plasma glucose >= 6.1 but <= 6.9 mmol/L

Non-fasting venous plasma glucose >= 7.8 but <= 11.0 mmol/L

HbA1c >= 39 but <= 47 mmol/mol

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12 exclusion criteria prevent from participating
T2D indicated by >= 2 of the following values, measured at different occasions or through different analyses

Fasting venous plasma glucose >= 7.0 mmol/L

Non-fasting venous plasma glucose value >= 11.1 mmol/L

HbA1c >= 48 mmol/mol

Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
OGTT at home then at the clinic

Group II

Experimental
OGTT at the clinic then at home

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 3 locations

Recruiting

Primary Health Care Center Bra Liv Rosenhälsan

Huskvarna, SwedenOpen Primary Health Care Center Bra Liv Rosenhälsan in Google Maps
Recruiting

Primary Health Care Center Cityhälsan Centrum

Norrköping, Sweden
Recruiting

Primary Care Center Vårdcentralen Kärna

Linköping, Sweden
Recruiting
3 Study Centers
OGTT-CGM | Home Glucose Tolerance Test Using Continuous Glucose Monitoring for Prediabetes | PatLynk