ePRONEProne Positioning in ARDS for Mortality Reduction

This clinical trial focuses on patients suffering from Acute Respiratory Distress Syndrome (ARDS), which is a serious lung condition with a high risk of death. The study aims to determine if keeping patients in a prone position (lying face down) continuously for longer periods can reduce mortality compared to the standard practice of daily prone sessions. The prone position is known to improve lung function and reduce the harm caused by mechanical ventilation. This study is particularly important for patients who require mechanical breathing support and have severe ARDS, as finding the best prone position technique could improve survival rates. The trial involves two groups of patients, randomly assigned to either continuous or intermittent prone positioning. Those in the continuous group stay in the prone position for at least 48 hours, up to a maximum of 120 hours, while those in the intermittent group follow the current standard of 16 to 24 hours per day. This approach allows researchers to compare the effects on survival rates and any potential side effects of each method. The goal is to see which method helps keep oxygen levels stable and reduces the chances of complications over a period of seven days. The outcome of this study could lead to improved treatment strategies for those with severe ARDS.