Norepinephrine vs Phenylephrine for Spinal Anesthesia-Induced Hypotension in Emergency Cesareans
Norepinephrine Bolus
+ Phenylephrine bolus
Prevention Study
Summary
Study start date: December 31, 2024
Actual date on which the first participant was enrolled.This study investigates how effective two different medications, norepinephrine and phenylephrine, are at preventing low blood pressure caused by spinal anesthesia during emergency cesarean sections. This complication, known as hypotension, is common and can be harmful to both the mother and baby. The study targets pregnant women who need an emergency C-section and are given spinal anesthesia. Understanding which medication better prevents low blood pressure could improve safety and outcomes for mothers and their newborns during surgery. Participants in the study are randomly assigned to receive either norepinephrine or phenylephrine through injections. Researchers monitor important health indicators like heart rate and blood pressure every three minutes. They also assess the newborn's health using the APGAR score right after birth. The study is conducted by healthcare professionals who collect and analyze data to determine the effectiveness of each drug in maintaining stable blood pressure during the procedure. This will help in deciding the best approach to manage anesthesia-induced hypotension in cesarean deliveries.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.124 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Prevention Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Female
Biological sex of participants that are eligible to enroll.From 18 to 40 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.2 intervention groups are designated in this study
This study does not include a placebo group
Treatment Groups
Group I
ExperimentalGroup II
Active ComparatorStudy Objectives
Primary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
Dr Ruth km pfau civil hospital karachi Dow University of health sciences, department of anesthesiology
Karachi, PakistanOpen Dr Ruth km pfau civil hospital karachi Dow University of health sciences, department of anesthesiology in Google Maps