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Rib Mobilization Impact on Ventilator Weaning for Pneumonia Patients

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What is being tested

rib mobilization technique

+ routine chest physiotherapy

Other
Who is being recruted

Infections+2

+ Lung Diseases

+ Pneumonia

From 40 to 50 Years
+11 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Interventional
Study Start: March 2025
See protocol details

Summary

Principal SponsorCairo University
Study Contacthoda gaber el said, masterMore contacts
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: March 10, 2025

Actual date on which the first participant was enrolled.

This study aims to explore a new method to help patients with pneumonia who are on a mechanical ventilator. Pneumonia can make the chest stiff and difficult to move, which can make breathing harder and slow down recovery. Ventilator-associated pneumonia is a common and serious problem in intensive care units. It can lead to longer hospital stays, higher risk of death, and increased healthcare costs. The study will compare two approaches: rib mobilization, which is a gentle technique to improve chest movement, and regular chest physiotherapy. The goal is to see if rib mobilization can help patients breathe more easily and reduce their time on a ventilator. In this study, patients with pneumonia who are on a ventilator will receive either rib mobilization or routine chest physiotherapy. Rib mobilization is a non-invasive technique that involves applying gentle pressure to the ribs to help them move better and improve breathing. The study will monitor how well each approach helps patients come off the ventilator, by measuring changes in their ability to breathe independently. There are no specific risks mentioned, but the potential benefit is finding a more effective way to improve breathing and recovery for patients with pneumonia on ventilators.

Official TitleEffect of Rib Mobilization on Weaning Parameters From Mechanical Ventilator in Patients With Pneumonia
NCT06835842
Principal SponsorCairo University
Study Contacthoda gaber el said, masterMore contacts
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

60 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 40 to 50 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

InfectionsLung DiseasesPneumoniaRespiratory Tract DiseasesRespiratory Tract Infections

Criteria

6 inclusion criteria required to participate
Patient's age ranged from 40- 50 years old from both genders.

Diagnosed with pneumonia and need invasive mechanical ventilation support.

Stable oxygen saturation (SpO2 more than 85, (FiO2) 0.6 or less, PEEP less than 10 Cm H2O).

mean arterial pressure > 75 mmHg and urine output > 1 mL/kg/h;

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5 exclusion criteria prevent from participating
Unstable hemodynamics

Unstable neurological problems e.g. (epileptic seizures -hyperthermia).

Unstable chest wall e.g. (multiple rib or vertebral fractures)

Increase intracranial pressure (>20 mmHg for >5 min).

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Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
1.rib mobilization technique and routine chest physio therapy group: the patients will receive rib mobilization technique in addition to their medical treatment and routine chest physiotherapy for at least 30 minutes once daily for ten consecutive days

Group II

Active Comparator
routine chest physiotherapy group : the patients in this group will receive routine chest physical therapy for at least 30 minutes once daily for 10 consecutive days

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

El Galaa Military Hospital

Cairo, EgyptOpen El Galaa Military Hospital in Google Maps
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One Study Center
Rib Mobilization Impact on Ventilator Weaning for Pneumonia Patients | PatLynk