REBOOSTDrug-Eluting Balloon vs. Paclitaxel Eluting Stent for Femoro-popliteal Lesions

This study focuses on comparing two different treatments for blockages in the arteries of the legs, specifically in the femoropopliteal region. These blockages are common in those with peripheral artery disease, affecting blood flow to the lower limbs. The study compares drug-eluting balloons (DCB) and self-expandable polymer-coated paclitaxel eluting stents (SEDES) as treatment options. Both methods have shown benefits in previous research, but there is still uncertainty about which is better. The goal is to determine which treatment is more effective and safer, which could lead to better care for patients with these artery blockages. Participants in the study will undergo a procedure where a small tube is inserted into the femoral artery to examine and treat the blockage. Initially, a balloon is used to open the artery, and if successful, patients will be randomly assigned to receive either the DCB or SEDES treatment. The study will involve careful monitoring at various intervals over two years to assess the effectiveness and safety of the treatments. Participants will take medication to prevent blood clots during and after the study. The results will help determine which treatment better maintains blood flow in the arteries without complications.