Biomarkers for Acute Kidney Injury in Cardiac Surgery Patients

Researchers aim to gain a deeper understanding of acute kidney injury that occurs after heart surgery, known as cardiac surgery-associated acute kidney injury (CSA-AKI). This condition is common among people who undergo heart surgeries, particularly affecting those who are older or have existing conditions like kidney disease or diabetes. The study focuses on identifying biological markers, or biomarkers, which are signs that can indicate how CSA-AKI develops, particularly in the crucial hours and days following surgery. By comparing these biomarkers in patients who do develop CSA-AKI with those who don't, researchers hope to pinpoint potential targets for preventing this complication in the future. Participants in this study are individuals scheduled for heart surgery who are at risk of developing CSA-AKI. They will not receive any experimental treatment as part of the study; instead, they will undergo their planned surgeries as usual. Researchers will collect blood and urine samples from participants before and after their surgeries. They will also review the participants' medical records and test results during their hospital stay. The study lasts up to two months, during which the health of the participants will be closely monitored to gather valuable data on the development of CSA-AKI.