Completed

PIHPLa Roche Posay Routine for Facial Post Inflammatory Hyperpigmentation

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What is being collected

Data Collection

Collected from today forward - Prospective
Who is being recruted

Acne Vulgaris+4

+ Pigmentation Disorders

+ Sebaceous Gland Diseases

From 18 to 50 Years
+21 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Cohort

Tracking disease incidence in order to identify risk factors and understand disease progression over time.
Observational
Study Start: February 2023
See protocol details

Summary

Principal SponsorCosmetique Active International
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: February 27, 2023

Actual date on which the first participant was enrolled.

The sample size of this study is 80 participants; 40 subjects testing Niacinamide A serum and UV Mune and 40 subjects testing Eucerin Thiamidol anti-pigment serum and Eucerin SPF 50+. The secondary objectives are: * the effect on the cutaneous acceptability by clinical examination under dermatological control * the effect of the product on acne lesions is assessed by comparing the number of elements on the face before application and after product use * the effect on acne severity according to the Global Acne Evaluation * the mean darkness of the post-inflammatory hyper-pigmentation (PIHP) lesions. A statistical analysis of the following will be done: a comparison of the before/after application, a comparison of the values obtained from the comparison product/comparator product, and a comparison PIHP lesion/normal zone. The study endpoints are: * global acne evaluation scale * mean size, intensity, number of PIHP lesion * mean darkness of lesions * subject global assessment score * improvement in scores in a stigmatization questionnaire * satisfaction questionnaire

Official TitleEfficacy of La Roche Posay Routine in the Management of Facial Post Inflammatory Hyperpigmentation (PIHP)
NCT06770127
Principal SponsorCosmetique Active International
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

80 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Cohort

These studies follow a group of individuals with common characteristics (such as a condition or birth year) over a specific period to study health outcomes or exposures.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 50 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Acne VulgarisPigmentation DisordersSebaceous Gland DiseasesSkin DiseasesSkin and Connective Tissue DiseasesAcneiform EruptionsHyperpigmentation

Criteria

4 inclusion criteria required to participate
Fitzpatrick skin phototype: III to VI;
Moderate to severe PIHP due to acne (score PAHPI > 10);
Subjects with mild acne on the face (GEA = 2);
≤ 4 inflammatory lesions total (non-inflammatory lesions could be 0)
17 exclusion criteria prevent from participating
Cosmetic product for non-comedogenicity within the last 2 weeks;
Subjects with symptoms of COVID-19 (moderate fever, dry cough and other symptoms described by the World Health Organization);
Subjects with a temperature above 37.5 °C;
COVID-19 positive patients;
Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Insight Research

Quatre Bornes, MauritiusOpen Insight Research in Google Maps
CompletedOne Study Center
PIHP | La Roche Posay Routine for Facial Post Inflammatory Hyperpigmentation | PatLynk