Completed

Plant-based Nootropic Supplement for Cognitive Enhancement

What is being tested

Nootropics (ginkgo biloba, nicergoline, piracetam, or others)

+ Perceptual decision-making performance

+ Electroencephalography

Dietary SupplementBehavioralDevice

Who is being recruted

From 20 to 59 Years

+2 Eligibility Criteria

See all eligibility criteria

How is the trial designed

Basic Science Study

Placebo-Controlled

Interventional

Study Start: October 2023

See protocol details

Summary

Principal SponsorUniversity of Leeds

Last updated: January 28, 2026

Sourced from a government-validated database.Claim as a partner

Study start date: October 23, 2023

Actual date on which the first participant was enrolled.

This study investigates the effects of a plant-based supplement, Mind Lab Pro, on how people make quick decisions based on what they perceive. It is aimed at understanding how this supplement might enhance brain function, particularly in the area of decision-making. By exploring these effects, the study hopes to provide insights that could lead to better cognitive enhancers, especially for individuals looking to boost their mental performance without the use of synthetic drugs. Participants in the study will take either the Mind Lab Pro supplement or a placebo, which is a substance with no active ingredients, every day for 60 days. They will also complete a computerized task designed to test decision-making abilities both before and after the supplementation period. Brain activity will be recorded using electroencephalography (EEG) to observe changes in brain function related to the supplement. This setup helps researchers identify any differences in cognitive performance and brain activity between the supplement and placebo groups.

Official TitleEffect of a Plant-based Nootropic Supplement on Perceptual Decision-making and Brain Network Interdependencies: a Randomised, Double-blinded and Placebo-controlled Study.

NCT06689644

Principal SponsorUniversity of Leeds

Last updated: January 28, 2026

Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Design Details

37 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Basic Science Study

Basic science studies help researchers understand how the body works or how a disease develops. They don't test treatments, but they build the foundation for future therapies.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.

Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 20 to 59 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Criteria

1 inclusion criteria required to participate

Eligibility screening of participants was guided by the following inclusion criteria: (i) be between 20-59 years old, (ii) be right-handed and (iii) be able to cease taking other dietary supplements for two months.

1 exclusion criteria prevent from participating

Exclusion criteria included: (i) currently consuming a nootropic supplement, (ii) any known musculoskeletal, or neurological medical conditions or cognitive impairments (iii) have a known diagnosis of epilepsy/history of seizures and (iv) have a known hearing or visual condition that affects daily life function.

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.

Treatment Groups

Study Objectives

2 intervention groups are designated in this study

50% chance of being blinded to the placebo group

Treatment Groups

Group I

Experimental

This group will receive the nootropic supplement for 60 days.

Group II

Placebo

This group will receive a placebo supplement for 60 days

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Faculty of Biological sciences

Leeds, United KingdomOpen Faculty of Biological sciences in Google Maps

CompletedOne Study Center