GEN1286 for Advanced Solid Tumors
GEN1286
Treatment Study
Summary
Study start date: November 13, 2024
Actual date on which the first participant was enrolled.This clinical trial is designed to study a new medication called GEN1286 for people with advanced solid tumors. Solid tumors are abnormal masses of tissue that usually don't contain cysts or liquid areas, and they can occur in various parts of the body, like the breast, lung, or liver. The study aims to determine if GEN1286 is safe and tolerable for patients, how the body processes the drug, and its potential to fight tumors. Additionally, researchers will observe if the drug causes any immune response. This study is important because finding effective treatments for advanced tumors can improve outcomes and provide new options for patients. Participants in the study will receive GEN1286 in two main phases. In the first part, the dose of GEN1286 will be gradually increased to identify the safest and most effective amount. Once an optimal dose is found, the second part will focus on specific types of tumors to further explore the drug's effects. Participants will be closely monitored to see how their bodies react to the treatment, and any changes in their tumors will be documented. The study seeks to understand the drug's properties thoroughly, including any potential risks or unexpected reactions.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.23 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.Over 18 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.One single intervention group is designated in this study
This study does not include a placebo group
Treatment Groups
Group I
ExperimentalStudy Objectives
Primary Objectives
Secondary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 4 locations
Massachusetts General Hospital
Boston, United StatesOpen Massachusetts General Hospital in Google MapsSTART Midwest
Grand Rapids, United StatesSTART San Antonio
San Antonio, United StatesSTART Mountain Region
West Valley City, United States