Vancomycin and Fecal Microbiota Transplant for Parkinson's Disease

This study is looking into the safety of using a treatment combination for adults with Parkinson's disease. It starts with a 10-day course of the antibiotic Vancomycin, followed by a procedure called a fecal microbiota transplant (FMT). The idea is to see if this combination can safely help people with Parkinson's disease, a condition that affects movement and motor skills. This study is important because it explores a potentially new way to care for Parkinson's disease by possibly improving gut health, which might have an effect on the disease's symptoms. Participants in the study will have several scheduled visits and procedures. They will first meet with the study doctor to discuss the study and have initial assessments. After taking Vancomycin, participants will prepare for the FMT procedure, which will be done through a colonoscopy at an outpatient center. Following the FMT, there are multiple follow-up visits to observe and assess participants' well-being. Daily phone check-ins will occur the week after FMT, and weekly calls are made for further monitoring. This approach ensures a comprehensive evaluation of any changes in health, medication, and side effects, aiming to ensure participant safety throughout the study.