Vaginal Washing Cessation Impact on Cervicovaginal Inflammation

This study investigates how vaginal washing might be connected to an increased risk of HIV, particularly among women involved in sex work in Mombasa, Kenya. The practice of vaginal washing, while often seen as hygienic, could disrupt the natural balance of bacteria in the vagina and cause inflammation, potentially making it easier for HIV to infect. The study aims to understand if stopping vaginal washing can reduce these risks by looking at changes in inflammation and bacteria in the vagina and cervix. Participants in the study will be part of a randomized trial where some will receive guidance on how to stop vaginal washing using a behavioral change model. Researchers will measure the levels of inflammation and the types of bacteria present in the vagina before and after the intervention. By examining these factors, the study hopes to identify the biological changes that occur when vaginal washing is reduced, potentially leading to better health outcomes and lower HIV risk.