Cilostazol Impact on Cognitive and Motor Symptoms in Parkinson's Disease
Cilostazol
+ Standard treatment
+ Placebo
Synucleinopathies+10
+ Neuroinflammatory Diseases
+ Basal Ganglia Diseases
Treatment Study
Summary
Study start date: October 1, 2024
Actual date on which the first participant was enrolled.This clinical trial is focused on evaluating the effects of the drug Cilostazol on patients with Parkinson's Disease. Parkinson's Disease is a progressive brain disorder that affects movement and can lead to cognitive decline. The disease is associated with the degeneration of dopamine-producing neurons and is influenced by factors like inflammation and oxidative stress. Cilostazol, which is already used to treat certain vascular conditions, has properties that could potentially protect brain cells by reducing inflammation and oxidative stress. This study is investigating whether Cilostazol can help slow down the progression of Parkinson's Disease and improve cognitive function in patients. Participants in the trial will receive Cilostazol, typically administered in pill form, to assess its impact on Parkinson's Disease symptoms and cognitive decline. The study will measure various outcomes, such as improvements in movement and cognitive abilities, to determine the drug's effectiveness. While Cilostazol has shown promise in preliminary studies, it is important to monitor for potential side effects, which can include headaches and gastrointestinal issues, among others. The goal of the study is to explore a novel treatment option that might offer better management of Parkinson's Disease symptoms and potentially slow its progression.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.50 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.2 intervention groups are designated in this study
This study does not include a placebo group
Treatment Groups
Group I
ExperimentalGroup II
Active ComparatorStudy Objectives
Primary Objectives
Secondary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location