Recruiting

SHR-7787 for Advanced Solid Tumors

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

SHR-7787 injection

Drug
Who is being recruted

From 18 to 75 Years
+18 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Phase 1 & 2
Interventional
Study Start: October 2024
See protocol details

Summary

Principal SponsorShanghai Hengrui Pharmaceutical Co., Ltd.
Study ContactKe Ma
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: October 4, 2024

Actual date on which the first participant was enrolled.

This clinical study is focused on patients with advanced solid tumors, aiming to assess a new treatment called SHR-7787. The primary goal is to determine how safe and tolerable this drug is when used alone, as well as to understand how the body processes it and whether it can effectively treat the tumors. By exploring the most suitable dosage, the study seeks to find out if SHR-7787 can become a viable treatment option, potentially offering hope for patients whose tumors are not responding to existing therapies. Participants in the study will receive SHR-7787 through an injection. Researchers will closely monitor the patients to observe any side effects and how well they tolerate the drug. They will also measure how the body absorbs, distributes, and eliminates the drug to understand its pharmacokinetics. While there are no specific outcomes listed, the study will likely evaluate changes in tumor size or progression to gauge the drug's effectiveness. Participants should be informed about potential risks and benefits, though specific details on these are not provided in the available information.

Official TitleA Phase I/II, Open Label, Multicenter Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of SHR-7787 in Patients With Advanced Solid Tumors
NCT06605222
Principal SponsorShanghai Hengrui Pharmaceutical Co., Ltd.
Study ContactKe Ma
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

201 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 75 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Criteria

6 inclusion criteria required to participate
Ability to understand and voluntarily agrees to participate by giving written informed consent for the study;

Patients with unresectable recurrent or metastatic solid tumors;

There is at least one lesion could be measured;

An Eastern Cooperative Oncology Group (ECOG) performance status (PS) score of 0 or 1;

Show More Criteria

12 exclusion criteria prevent from participating
Patients with known active central nervous system (CNS) metastases;

Subjects who had other malignancy in five years before the first dose;

Patients with tumor-related pain that cannot be controlled as determined;

Patients with serious cardiovascular and cerebrovascular diseases;

Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

Shanghai Pulmonary Hospital

Shanghai, ChinaOpen Shanghai Pulmonary Hospital in Google Maps
Recruiting
One Study Center