DRINKSaline vs. Ringer Lactate for Severe Diabetic Ketoacidosis

This clinical trial is aimed at finding out whether using a solution called Ringer Lactate is more effective and safer than the commonly used isotonic saline for treating people with severe diabetic ketoacidosis. Diabetic ketoacidosis is a serious condition that occurs when the body starts breaking down fats at a rapid rate, leading to a buildup of acids in the bloodstream called ketones. Isotonic saline, though widely used, can sometimes lead to complications like an imbalance of acids and bases in the body or kidney problems. Ringer Lactate has a composition closer to the body's natural fluids, potentially offering a safer alternative. This study is important as it seeks to improve the treatment of diabetic ketoacidosis by possibly providing a better fluid option that reduces the risk of complications. In this study, participants with severe diabetic ketoacidosis will receive either Ringer Lactate or isotonic saline. The solutions are given as fluids through a vein, a common method known as fluid resuscitation. The trial is designed to carefully measure how quickly the diabetic ketoacidosis resolves in each group and to check for any side effects related to the fluids used. By comparing the two solutions in a controlled setting, the study aims to determine if Ringer Lactate can lead to faster recovery and fewer complications than isotonic saline. The goal is to provide clearer guidance on the best fluid choice for managing this condition.