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CH1Pelvic Floor Exercises for Preventing LARS After Rectal Cancer Surgery

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Study Aim

This study aims to see if doing pelvic floor exercises at home can prevent or reduce bowel problems in people after rectal cancer surgery.

What is being tested

Pelvic floor exercise

Procedure
Who is being recruted

Urogenital Diseases+19

+ Low Anterior Resection Syndrome

+ Colonic Diseases

Over 19 Years
+6 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Prevention Study

Interventional
Study Start: April 2024
See protocol details

Summary

Principal SponsorF. D. Roosevelt University Hospital
Study ContactBarbara Mrázová, MD,MPHMore contacts
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: April 1, 2024

Actual date on which the first participant was enrolled.

This study focuses on preventing a condition called Low Anterior Resection Syndrome (LARS) in patients who have undergone minimally invasive surgery for rectal cancer. LARS can cause problems like urgency, loss of bowel control, and constipation, significantly affecting quality of life. Pelvic floor exercises, which strengthen the muscles supporting organs in the lower body, may help prevent these issues. However, there are not many studies that confirm this benefit. The goal of this research is to explore whether these exercises can effectively reduce the risk of LARS, potentially improving the well-being of patients after surgery. Participants in the study will engage in a regimen of pelvic floor exercises following their rectal cancer surgery. The study will observe the effects of these exercises over time to determine their impact on preventing LARS. While the exercises are generally safe, the study aims to measure their effectiveness in maintaining bowel function and improving life quality for patients. The findings could lead to better recommendations for managing post-surgery complications, offering a non-invasive way to enhance recovery and prevent long-term issues.

Official TitleEffectiveness of Pelvic Floor Exercise to Prevent LARS (Low Anterior Resection Syndrome) After Mini-invasive Low Anterior Resection in Patients With Rectal Cancer
NCT06519006
Principal SponsorF. D. Roosevelt University Hospital
Study ContactBarbara Mrázová, MD,MPHMore contacts
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

50 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Prevention Study

Prevention studies aim to stop a disease from developing. They often involve people at risk and test things like vaccines, lifestyle changes, or preventive medications.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 19 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Urogenital DiseasesLow Anterior Resection SyndromeColonic DiseasesDigestive System DiseasesDigestive System NeoplasmsFemale Urogenital Diseases and Pregnancy ComplicationsGastrointestinal DiseasesGastrointestinal NeoplasmsIntestinal DiseasesIntestinal NeoplasmsNeoplasmsNeoplasms by SitePathologic ProcessesPostoperative ComplicationsPregnancy ComplicationsRectal DiseasesRectal NeoplasmsPathological Conditions, Signs and SymptomsColorectal NeoplasmsFemale Urogenital DiseasesMale Urogenital DiseasesPelvic Floor Disorders

Criteria

2 inclusion criteria required to participate
Cognitive functions make it possible to understand and sign the patient's informed consent and consent to participate in the study

Surgical procedure - mini-invasive low anterior rectal resection

4 exclusion criteria prevent from participating
not agreeing to participate in the study

request to practice pelvic floor exercises despite being in the control group

non-compliance

serious psychiatric diagnoses

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
This arm will be instructed to exercise pelvic floor after low anterior resection for one month and 1, 6, and 12 months postoperatively will be questioned about the possible development of LARS. One month after surgery they will also be questioned about adherence to prescribed exercise.

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

F.D.Roosevelt University Hospital in Banská Bystrica

Banská Bystrica, SlovakiaOpen F.D.Roosevelt University Hospital in Banská Bystrica in Google Maps
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One Study Center