IMPROVELow-Dose Ketamine for Pain Relief in Burn Wound Care

This study is looking at how a low dose of ketamine, given through an infusion, might help people with burn injuries feel less pain during wound care procedures. The usual pain relief medications, like fentanyl and midazolam, don't always work well enough on their own. This research aims to see if ketamine can make a difference by improving pain relief and potentially reducing the need for opioids, which can have serious side effects. This study is important as it seeks to find better ways to manage pain for burn patients, which can improve their overall recovery experience. Participants in the study will receive either a low dose of ketamine or a placebo while undergoing their regular burn wound care. The ketamine or placebo is administered through an infusion, which means it is delivered directly into the bloodstream. The study will measure how well the ketamine reduces pain during these procedures and whether it leads to a decrease in the use of opioids. By evaluating the pain levels and opioid consumption, researchers aim to determine if ketamine can be a safer and more effective option for managing pain in burn patients.