APDT-T2DAntibacterial Photodynamic Therapy for Diabetic Periodontitis
This study aims to evaluate whether antibacterial photodynamic therapy can reduce bleeding in the gums of people with diabetic periodontitis.
Lumoral Treatment
+ Standard oral hygiene
Diabetes Mellitus+9
+ Diabetes Mellitus, Type 2
+ Endocrine System Diseases
Treatment Study
Summary
Study start date: January 23, 2025
Actual date on which the first participant was enrolled.This study explores a new way to manage and prevent gum disease, known as periodontitis, in people with diabetes. High blood sugar levels can increase the risk of periodontitis, while untreated gum disease can worsen blood sugar control. The study aims to improve access to oral healthcare for diabetic patients, focusing on early detection and prevention of oral diseases. It emphasizes the importance of collaboration between diabetes care and oral health services. This approach could help manage both diabetes and gum disease more effectively, improving overall health outcomes and potentially creating cost-effective preventive care pathways. Participants in the study will use a home-based photodynamic therapy, known as aPDT, which involves using dual light therapy to treat gum disease. Additionally, a special test called the aMMP-8 test will be used to assess the risk of periodontal disease and monitor treatment success. This test can activate certain enzymes to provide real-time information about inflammation and help determine how often maintenance treatments are needed. Participants will also be encouraged to improve their oral self-care at home, as this plays a crucial role in preventing oral diseases. The study aims to show that this combination of treatments can improve outcomes for diabetic patients with periodontitis.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.150 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.Over 18 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.2 intervention groups are designated in this study
This study does not include a placebo group
Treatment Groups
Group I
ExperimentalGroup II
Active ComparatorStudy Objectives
Primary Objectives
Secondary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
Wellbeing Services of County Pirkanmaa
Tampere, FinlandOpen Wellbeing Services of County Pirkanmaa in Google Maps