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CIMTCIMT and NDT for Stroke Upper Extremity Rehabilitation

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Study Aim

This study aims to evaluate the effectiveness of Constraint-Induced Movement Therapy and Neuro-Developmental Treatment in improving upper arm and hand function in stroke patients.

What is being tested

Constraint-induced movement therapy

+ Neurodevelopmental Treatment

Other
Who is being recruted

Ischemic Stroke+6

+ Thrombotic Stroke

+ Brain Diseases

From 40 to 65 Years
+2 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Interventional
Study Start: June 2024
See protocol details

Summary

Principal SponsorShalamar Institute of Health Sciences
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: June 28, 2024

Actual date on which the first participant was enrolled.

The study is focused on comparing two different rehabilitation methods, CIMT (Constraint-Induced Movement Therapy) and NDT (Neurodevelopmental Treatment), to help stroke patients regain function in their arms and hands. By adding these techniques to regular physiotherapy, the research aims to find the most effective way to improve movement and strength in the upper body. This is important because better rehabilitation strategies can significantly impact the recovery and quality of life for those who have suffered a stroke, allowing them to perform daily activities more independently. Participants in this study will undergo sessions involving CIMT or NDT alongside standard physiotherapy exercises. CIMT involves using the affected limb more actively by restricting the use of the unaffected limb, while NDT focuses on improving movement patterns and muscle control through guided exercises. Researchers will evaluate the progress of participants by measuring improvements in their arm and hand functions. The study seeks to determine which method offers better results, ultimately guiding therapists in choosing the best approach to help stroke survivors recover more efficiently.

Official TitleComparison Between the Efficacy of CIMT and NDT Along With Conventional Physiotherapy Treatment on Upper Extremity Rehabilitation Among Patients of Stroke
NCT06485583
Principal SponsorShalamar Institute of Health Sciences
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

10 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 40 to 65 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Ischemic StrokeThrombotic StrokeBrain DiseasesCardiovascular DiseasesCentral Nervous System DiseasesCerebrovascular DisordersNervous System DiseasesVascular DiseasesStroke

Criteria

1 inclusion criteria required to participate
Participants will be aged 40-65 years and will have experienced either a hemorrhagic or ischemic stroke with hemiplegic presentation within the past 1 to 6 months. Additionally, they must have a Mini-Mental State Examination (MMSE) score of 23.

1 exclusion criteria prevent from participating
Participants with visual or auditory deficits, musculoskeletal (MSK) disorders, mental impairments, or a history of surgery will be excluded from the study.

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

The rehabilitation plan involves several components to promote the recovery of the affected limb. Initially, we will immobilize the unaffected limb using a constraint device such as a mitt or sling for about 90% of waking hours over a period of six weeks.

Group II

The rehabilitation approach includes hands-on techniques to guide the patient through normal movement patterns. By providing sensory input, we aim to improve motor control and postural alignment, using techniques such as handling, guiding, and assisting movements.

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Ayesha Fatima

Lahore, PakistanOpen Ayesha Fatima in Google Maps
Recruiting soonOne Study Center