Completed

CREATINE_TENCreatine Supplementation for Athletes with Patellar Tendinopathy

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Study Aim

This study assesses the impact of creatine supplementation on pain and tendon thickness in athletes suffering from patellar tendinopathy.

What is being tested

Creatine supplementation

+ Placebo

Dietary Supplement
Who is being recruted

Wounds and Injuries

From 18 to 49 Years
+10 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Placebo-Controlled
Interventional
Study Start: January 2021
See protocol details

Summary

Principal SponsorUniversidad Pontificia Comillas
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: January 1, 2021

Actual date on which the first participant was enrolled.

This study focuses on understanding how creatine supplements, when used alongside a specific rehabilitation program, can help athletes dealing with patellar tendinopathy, a condition that affects the tendon below the kneecap. The goal is to see if creatine can reduce pain, improve the tendon’s health, and enhance muscle strength and athletic performance, particularly in jumping. The study targets athletes undergoing rehabilitation, which includes exercises that stretch and strengthen the muscles and tendons, as well as treatments like extracorporeal shock wave therapy. This research is important because it could lead to more effective recovery strategies for athletes, helping them return to their sport more quickly and with a lower risk of re-injury. Participants in the study will take creatine supplements while following a structured rehabilitation program. This program includes exercises that focus on building strength and flexibility, alongside special treatments to stimulate healing. Researchers will assess various outcomes, such as changes in pain levels, tendon health, body composition, muscle strength, and jumping ability. By measuring these factors, the study aims to determine whether creatine can enhance the rehabilitation process, potentially offering a simple yet effective way to boost recovery from tendon injuries in athletes.

Official TitleEffects of Creatine Supplementation in Combination With a Rehabilitation Program Physical in Athletes With Patellar Tendinopathy
NCT06482619
Principal SponsorUniversidad Pontificia Comillas
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

26 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Male

Biological sex of participants that are eligible to enroll.

From 18 to 49 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Wounds and Injuries

Criteria

7 inclusion criteria required to participate
Athletes diagnosed with patellar tendinopathy by sport medicine doctor.

Age (>18 years and <49 years).

To be federated in a sport modality that involves high repetitive impact in the knee; iii) to train more than 3 sessions weekly.

Not having undergone knee surgery.

Show More Criteria

3 exclusion criteria prevent from participating
Not being diagnosed with patellar tendinopathy by a doctor

Age (<18 years and > 50 years).

Involved in a sport modality without high repetitive impacts during sports activity.

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

50% chance of being blinded to the placebo group

Treatment Groups

Group I

Experimental
Creatine monohydrate (Creapure®, Crown Sport Nutrition, Arnedo, Spain) ingested 3 capsules daily (3 g/day)

Group II

Placebo
Sucrose ingested 3 capsules daily (3 g/day)

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Universidad Pontificia Comillas

Madrid, SpainOpen Universidad Pontificia Comillas in Google Maps
CompletedOne Study Center