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PRP vs Corticosteroid Injection Effectiveness in Pes Anserinus Pain Syndrome

Study Aim

This study aims to compare the effectiveness of PRP (Platelet Rich Plasma) and Corticosteroid injections in relieving pain for individuals suffering from Pes Anserinus Pain Syndrome, using a Visual Analogue Scale (VAS) for measurement.

What is being tested

PRP injection

+ corticosteroid injection

Drug

Who is being recruted

Bursitis

+ Joint Diseases

+ Musculoskeletal Diseases

Over 18 Years

+10 Eligibility Criteria

See all eligibility criteria

How is the trial designed

Treatment Study

Interventional

Study Start: July 2024

See protocol details

Summary

Principal SponsorRamathibodi Hospital

Study ContactThaned ekthanapornMore contacts

Last updated: January 28, 2026

Sourced from a government-validated database.Claim as a partner

Study start date: July 1, 2024

Actual date on which the first participant was enrolled.

This clinical trial is focused on finding the best treatment for patients with pes anserinus bursitis, a condition that causes knee pain and discomfort. The study takes place at Ramathibodi Hospital and aims to compare the effectiveness of two different types of injections: Platelet-rich Plasma (PRP) and corticosteroids. Pes anserinus bursitis often leads to pain and difficulty in movement, so discovering a more effective treatment could greatly improve the quality of life for those affected by this condition. Participants in the study are randomly assigned to receive either a PRP injection or a corticosteroid injection, both of which are administered by an orthopedic surgeon using ultrasound guidance. The trial uses a method where neither the participants nor the person assessing the outcomes know which treatment the participants received, thereby ensuring unbiased results. The effectiveness of the treatments is measured using a Visual Analogue Scale (VAS) and WOMAC scores to evaluate pain and movement ability. Follow-up assessments occur at 4, 12, and 24 weeks after the injection to track progress and outcomes over time.

Official TitleEfficacy of Platelet-rich Plasma Injection Compare With Corticosteroid in Pes Anserinus Pain Syndrome, Randomized Controlled Trial Study

NCT06453603

Principal SponsorRamathibodi Hospital

Study ContactThaned ekthanapornMore contacts

Last updated: January 28, 2026

Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Design Details

24 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.

Conditions

Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

BursitisJoint DiseasesMusculoskeletal Diseases

Criteria

3 inclusion criteria required to participate

Over 18 years old

Patients diagnosed with Pes Anserine Pain Syndrome

Patients willing to participate in the research project by signing a consent form

7 exclusion criteria prevent from participating

Patients with a localized knee infection or a disseminated infection within the past 3 months

Patients with thyroid disorders, rheumatoid arthritis, or other types of knee arthritis

Patients with abnormal blood coagulation or thrombocytopenia

Patients who are pregnant

Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.

Treatment Groups

Study Objectives

2 intervention groups are designated in this study

This study does not include a placebo group

Treatment Groups

Group I

Experimental

receive pes anserinus PRP injection

Group II

Active Comparator

receive pes anserinus corticosteroid injection

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has no location dataSave this study to your profile to know when the location data is available.

Recruiting soonNo study centers