HaemodialysisImpact of Vitamin B12 Deficiency on Anemia and Neuropathy in Chronic Haemodialysis Patients

This study focuses on Vitamin B12 deficiency and its impact on patients undergoing chronic haemodialysis, a treatment for kidney failure. Vitamin B12 plays a crucial role in several body functions, including the health of the nervous system, the formation of red blood cells, and DNA synthesis. Low levels of Vitamin B12 can lead to high concentrations of a substance called homocysteine, which can cause health complications. One of these complications is cardiovascular disease, where Vitamin B12 and other B vitamins are believed to help reduce the risk by lowering homocysteine levels. Additionally, Vitamin B12 deficiency can cause a type of anemia characterized by larger than normal red blood cells, known as Macrocytic anemia. The study aims to understand how this deficiency affects patients on haemodialysis, particularly in relation to anemia and neuropathy, a type of nerve damage. In this observational study, participants' Vitamin B12 levels will be evaluated through serum tests, a common type of blood test. The primary outcome measured is the level of Vitamin B12 in the serum. This will help researchers understand the prevalence and impact of Vitamin B12 deficiency in this patient population. The study does not involve any treatment or intervention, but rather observes and measures the existing conditions and outcomes.