Completed

Efficacy of Locally Delivered Coconut Oil in Management of Stage II and III Grade B Periodontitis. A Randomized Controlled Clinical Trial

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What is being tested

topical application of coconut oil

+ scaling and debridement

BiologicalOther
Who is being recruted

Stomatognathic Diseases+1

+ Mouth Diseases

+ Periodontal Diseases

From 35 to 60 Years
+7 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Phase 1
Interventional
Study Start: February 2022
See protocol details

Summary

Principal SponsorMisr University for Science and Technology
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: February 15, 2022

Actual date on which the first participant was enrolled.

This study aims to explore how effective coconut oil is in treating a common gum disease called periodontitis, specifically in its moderate stages known as Stage II and III Grade B. Periodontitis is an inflammation of the tissues around the teeth, often caused by harmful bacterial buildup, affecting many people globally. The study is particularly important as it investigates whether adding coconut oil, known for its anti-inflammatory properties, to standard dental cleaning procedures can improve treatment outcomes. This approach could potentially offer a natural, effective way to enhance oral health care for those suffering from this condition. Participants in the study will undergo standard dental treatments, which include cleaning and removing plaque and tartar from the teeth. Some participants will also receive coconut oil applied directly to their gums as an additional treatment. The study will measure the effectiveness of this combined approach by observing changes in gum health and inflammation levels. The goal is to determine if the coconut oil enhances the effectiveness of traditional treatments, offering a new method to manage this common dental issue.

Official TitleEfficacy of Locally Delivered Coconut Oil in Management of Stage II and III Grade B Periodontitis. A Randomized Controlled Clinical Trial
NCT06384638
Principal SponsorMisr University for Science and Technology
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

34 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.


Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 35 to 60 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Stomatognathic DiseasesMouth DiseasesPeriodontal DiseasesPeriodontitis

Criteria

3 inclusion criteria required to participate
patients age group >35 years without ant systemic disease

Willing to take part in the study. Patients with more than 16 natural teeth and have test teeth with both mesial and distal neighboring teeth with periodontitis with clinical attachment loss >3 mm and radiographic percentage of bone loss/age ranged between 0.25 to 1.

Patients with no history of allergies to coconut

4 exclusion criteria prevent from participating
smokers

pregnant

lactating women

Teeth with both endodontic-periodontal lesion.

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Active Comparator
coconut oil as topical application as adjunctive to scaling and root debridement

Group II

Active Comparator
scaling and root debridement

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Faculty of dentistry at MUST

Giza, EgyptOpen Faculty of dentistry at MUST in Google Maps
CompletedOne Study Center