Effect of Dapagliflozin on Body Weight in Overweight Women Consuming Different Proportions of Carbohydrate Diet.

This study is focused on understanding how a medication called dapagliflozin can help overweight women lose weight, especially when they consume different amounts of carbohydrates in their diets. Around 36 women who are overweight will participate in this trial. Initially, they will follow their usual eating habits for four weeks. If their weight doesn't change much during this period, they will continue into the next phase. The goal is to explore how effective dapagliflozin is at promoting weight loss, potentially offering a new way to manage weight, especially for those struggling with obesity. Participants will take dapagliflozin tablets by mouth once a day for 12 weeks while continuing their normal diet. To monitor progress, they will keep a detailed food diary three times a week. Researchers will collect various health indicators, including blood pressure, blood sugar levels, body measurements, and urine samples, to see how the medication affects their weight and overall health. Additionally, the study will examine the participants' gut bacteria by analyzing stool samples. Participants are divided into two groups based on their carbohydrate intake to see if the amount of carbohydrates they eat influences the effectiveness of the treatment. This study will help understand any potential side effects or benefits of using dapagliflozin for weight loss in women.