Recruiting

Over70-LTProspective Evaluation of a Selection Protocol for Patients Over 70 Years Old for Liver Transplantation

What is being collected

Data Collection

Collected from today forward - Prospective

Who is being recruted

Digestive System Diseases+2

+ Liver Diseases

+ Liver Failure

From 71 to 75 Years

+8 Eligibility Criteria

See all eligibility criteria

How is the trial designed

Cohort

Tracking disease incidence in order to identify risk factors and understand disease progression over time.

Observational

Study Start: October 2022

See protocol details

Summary

Principal SponsorAzienda Ospedaliera di Padova

Study ContactUmberto Cillo, ProfMore contacts

Last updated: January 28, 2026

Sourced from a government-validated database.Claim as a partner

Study start date: October 1, 2022

Actual date on which the first participant was enrolled.

Increased life expectancy and aging population has led to a trend of increasing liver transplant (LT) volume in the elderly. Nowadays, advanced age is not considered an absolute contraindication for LT but elderly LT candidates typically have an age-associated burden of comorbid conditions that can pose several clinical challenges during the selection/evaluation process for LT. Specific algorithms for elderly patient selection for LT are not well established; however, consensus agreement is that elderly LT candidates need a more rigorous selection process. This study proposes a "step by step" algorithm of selection for liver transplant candidates more than 70 years.

Official TitleProspective Evaluation of a Selection Protocol for Patients Over 70 Years Old for Liver Transplantation

NCT06382740

Principal SponsorAzienda Ospedaliera di Padova

Study ContactUmberto Cillo, ProfMore contacts

Last updated: January 28, 2026

Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Design Details

18 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Cohort

These studies follow a group of individuals with common characteristics (such as a condition or birth year) over a specific period to study health outcomes or exposures.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.

Conditions

Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 71 to 75 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Digestive System DiseasesLiver DiseasesLiver FailureHepatic InsufficiencyEnd Stage Liver Disease

Criteria

4 inclusion criteria required to participate

Age >70 years and ≤ 75 years

Liver transplant from cadaveric donor

First liver transplant

End stage liver disease or liver tumor

4 exclusion criteria prevent from participating

Age ≤ 70 years

Living donor liver transplant

Previous liver transplant

Liver transplant for acute liver failure

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

U.O.C Chirurgia Epatobiliare e Trapianti Epatici, Azienda Ospedaliera di Padova

Padua, ItalyOpen U.O.C Chirurgia Epatobiliare e Trapianti Epatici, Azienda Ospedaliera di Padova in Google Maps

Recruiting

One Study Center