Safety and Efficacy of Endobronchial Valve for Bronchoscopic Lung Volume Reduction Surgery: a Prospective Pilot Study

This study focuses on evaluating a new surgical method for people with chronic obstructive pulmonary disease (COPD) who have a type of condition called emphysema. It aims to see if using specially designed endobronchial valves during a procedure called lung volume reduction surgery can help improve lung function, increase exercise capacity, and reduce symptoms in these patients. Understanding the effectiveness and safety of these valves could offer a new way to manage emphysema, potentially providing relief for those who struggle with breathing difficulties related to this condition. Participants in this study will undergo a procedure where these endobronchial valves are placed into their lungs through a tube inserted via the mouth or nose. The study will monitor participants before the surgery and then at intervals of 3 days, 4 weeks, and 12 weeks afterward to see how their lung function and exercise capacities have changed, as well as to record any side effects from the surgery. This will help determine whether this new approach can be safely and effectively used as a treatment option for those living with emphysema.