Suspended

Open-Label Trial of Personalized Medication Experiments to Inform Decisions About Future Attention-Deficit/Hyperactivity Disorder (ADHD) Medication Use

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What is being tested

Personalized ADHD Medication Experiment

Other
Who is being recruted

Attention Deficit Disorder with Hyperactivity+1

+ Mental Disorders

+ Attention Deficit and Disruptive Behavior Disorders

From 11 to 15 Years
+11 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Services Research Study

Interventional
Study Start: November 2023
See protocol details

Summary

Principal SponsorChildren's Hospital Medical Center, Cincinnati
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: November 10, 2023

Actual date on which the first participant was enrolled.

This study aims to help families with adolescents who have ADHD make informed decisions about their ongoing medication use. Many families face uncertainty about whether to continue, change, or stop their child's ADHD medication. This trial focuses on adolescents who are currently taking stimulant ADHD medications. By exploring different medication use patterns, the study seeks to provide valuable insights that can guide future medication decisions and improve the management of ADHD symptoms. Participants in the study, which include 30 adolescents and their parents, will be involved in choosing one of five different medication experiments. This includes options like continuing current medication, changing the days they take the medication, stopping it temporarily, or adjusting the dose or type of medication. Families will track the effects of these changes over a set period. The study measures the impact by reviewing how these changes affect the adolescents' symptoms and overall management of ADHD. After completing the experiment, families will discuss their experiences and results with the study team to determine the best course of action for future medication use. No specific risks or benefits are detailed beyond gaining a better understanding of medication effects.

Official TitleOpen-Label Trial of Personalized Medication Experiments to Inform Decisions About Future Attention-Deficit/Hyperactivity Disorder (ADHD) Medication Use
NCT06305078
Principal SponsorChildren's Hospital Medical Center, Cincinnati
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

30 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Services Research Study

These studies look at how healthcare is delivered, managed, and organized. They aim to improve care quality, patient experience, and access to treatment.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 11 to 15 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Attention Deficit Disorder with HyperactivityMental DisordersAttention Deficit and Disruptive Behavior DisordersNeurodevelopmental Disorders

Criteria

8 inclusion criteria required to participate
Consent: A parent or legal guardian must provide written informed consent
Assent: Adolescents must provide written assent to participate in the study
Ages 11-15
Treated for ADHD by pediatrician
Show More Criteria
3 exclusion criteria prevent from participating
Do not have reliable access to the internet at their home or another location.
Will not permit their child to access the internet for study related activities.
Are not able or willing to send or receive text messages.

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
All will choose one of five medication experiment options to complete.

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Cincinnati Children's Hospital Medical Center

Cincinnati, United StatesOpen Cincinnati Children's Hospital Medical Center in Google Maps
SuspendedOne Study Center