Point of Care Test of LTA Level in Tear Fluid, Measured With a POCT Test, in DE Patients Following IPL Treatment
M22
+ sham M22
Eye Diseases
+ Lacrimal Apparatus Diseases
+ Dry Eye Syndromes
Treatment Study
Summary
Study start date: February 22, 2024
Actual date on which the first participant was enrolled.This study focuses on understanding how Intense Pulsed Light (IPL) treatment can help people with dry eye disease, particularly those caused by Meibomian gland dysfunction (MGD), which is a common form of dry eye. Dry eye can cause symptoms like eye pain, blurry vision, and tear film problems, often due to factors like aging, menopause, or certain medications. IPL has been used for skin conditions and is now being explored as a treatment for dry eye, potentially helping by reducing inflammation and improving tear quality. This study is important as it aims to evaluate the effectiveness of IPL in treating dry eye by looking at levels of a protein called Lymphotoxin-alpha (LTA) in tears, which might be a marker for dry eye severity and treatment response. In the study, participants with dry eye will receive IPL treatment. Researchers will collect tear samples to measure levels of LTA before and after the IPL sessions, using a special test designed to be quick and easy to use. This will help to see if the treatment affects the amount of LTA, providing insight into how IPL might help reduce dry eye symptoms. The study does not list specific risks or benefits but aims to provide clearer evidence for using IPL as a treatment option, potentially offering a more practical approach for managing dry eye in clinical settings.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.30 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.From 18 to 90 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.2 intervention groups are designated in this study
50% chance of being blinded to the placebo group
Treatment Groups
Group I
ExperimentalGroup II
ShamStudy Objectives
Primary Objectives
Secondary Objectives