Low Dose Aspirin for Prevention of Early Pregnancy Loss in Women at High Risk of Preeclampsia

This study explores whether taking a low-dose aspirin (81 mg daily) before the 16th week of pregnancy can reduce early pregnancy loss in women who are at high risk of developing preeclampsia. Preeclampsia is a pregnancy complication characterized by high blood pressure and can cause serious health issues for both the mother and the baby. Women with conditions such as diabetes, hypertension, or those expecting multiple babies are more susceptible to this condition. Since preeclampsia is linked to problems with the development of the placenta and inflammation, researchers are interested in seeing if aspirin, which can help with these issues, might also prevent early pregnancy loss. Participants in this study will be randomly assigned to receive either the low-dose aspirin or a placebo, which is a substance with no active medicine, to ensure that the results are unbiased. The study is double-blind, meaning neither the participants nor the researchers will know who is receiving the aspirin and who is receiving the placebo, which helps ensure the accuracy of the results. The main focus is to see if taking aspirin reduces the rate of early pregnancy loss among these high-risk women. While aspirin is generally considered safe in low doses, participants will be monitored for any side effects or complications during the study.