Recruiting soon

Protocol for The Lipid Registry of Africa (LIPRA)

What is being collected

Data Collection

Collected from today forward - Prospective

Who is being recruted

Arterial Occlusive Diseases+5

+ Arteriosclerosis

+ Cardiovascular Diseases

Until 65 Years

+7 Eligibility Criteria

See all eligibility criteria

How is the trial designed

Case-Only

Examining characteristics of individuals with a disease in order to identify genetic or environmental factors contributing to the condition.

Observational

Study Start: April 2024

See protocol details

Summary

Principal SponsorEuropean Atherosclerosis Society

Study ContactAshraf Reda, MD

Last updated: January 28, 2026

Sourced from a government-validated database.Claim as a partner

Study start date: April 30, 2024

Actual date on which the first participant was enrolled.

The Lipid Registry of Africa (LIPRA) aims to understand why some individuals in Africa experience heart issues at a younger age than others. The study investigates factors causing heart problems in younger adults, particularly acute coronary syndrome (ACS). Acute coronary syndrome (ACS) includes various heart conditions like unstable angina and heart attacks. Researchers from multiple African countries collaborate to gather information from hospitals across the region. They focus on patients under 55 years (men) or 65 years (women) with heart issues. Additionally, the study wants to compare different groups-men and women, urban and rural residents-to see if there are specific differences in how heart problems develop among them.

Official TitleProtocol for The Lipid Registry of Africa (LIPRA)

NCT06238375

Principal SponsorEuropean Atherosclerosis Society

Study ContactAshraf Reda, MD

Last updated: January 28, 2026

Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Design Details

4000 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Case-only

These studies focus only on individuals who have a specific disease. Researchers examine patterns—often genetic or environmental—to uncover what might be linked to the condition.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.

Conditions

Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Until 65 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Arterial Occlusive DiseasesArteriosclerosisCardiovascular DiseasesHeart DiseasesVascular DiseasesMyocardial IschemiaAtherosclerosisAcute Coronary Syndrome

Criteria

4 inclusion criteria required to participate

Individuals diagnosed with premature Acute Coronary Syndrome (ACS) within the defined age range (≤55 years in men and ≤65 years in women).

Patients admitted to designated cardiac facilities in Africa (Urban and rural).

Diagnosed cases of ST-elevation myocardial infarction (STEMI) or non-ST-elevation myocardial infarction/unstable angina pectoris (NSTEMI/UAP) based on predetermined criteria including symptoms, electrocardiogram (ECG) alterations, and biomarker levels.

Patients exhibiting an increase (above the 95th percentile) or decrease in serum troponin levels as per admission standards.

3 exclusion criteria prevent from participating

Individuals outside the defined age range for premature Acute Coronary Syndrome (ACS) diagnosis.

Patients not admitted to designated cardiac facilities in Africa.

Diagnosed cases not meeting the specified criteria for Acute Coronary Syndrome (ACS) subtypes (STEMI, NSTEMI/UAP) based on symptoms, electrocardiogram (ECG), and biomarker levels.

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has no location dataSave this study to your profile to know when the location data is available.

Recruiting soonNo study centers