A Single-Center, Open Label, Phase 4 Study of the Safety and Efficacy of Fixed Combination Phenylephrine 2.5%-Tropicamide 1% Ophthalmic Solution (Mydcombi®) Administered With the Mydcombi Dispenser for Pupil Dilation (THE MIST-2.1 STUDY)

This study focuses on testing a medicine called MydCombi, which is used to make the pupils of the eyes larger, a process known as mydriasis. This is important for eye exams and other diagnostic procedures where doctors need a better view inside the eye. The study is particularly interested in finding out if using half the usual dose of MydCombi, which is just one spray per eye instead of two, is still effective for pupil dilation. This research might help improve patient comfort and reduce medication use during eye examinations. Participants in the study will receive a single spray of MydCombi directly onto the cornea of each eye. The goal is to observe how well the pupils dilate with this reduced dosage. Although no specific outcomes are listed, the study will likely monitor the degree and duration of pupil dilation and any side effects that may occur. This approach aims to establish whether a lower dose can still achieve the desired dilation safely and effectively.