Investigation of the Effect of Pomegranate Supplementation on Symptom Severity in Women With Premenstrual Syndrome: A Randomized Controlled Trial
pomegranate extract
Menstruation Disturbances+1
+ Pathologic Processes
+ Premenstrual Syndrome
Supportive Care Study
Summary
Study start date: January 2, 2024
Actual date on which the first participant was enrolled.This study focuses on exploring how taking pomegranate supplements might help women who experience premenstrual syndrome (PMS), a common issue affecting many women of childbearing age. PMS can cause a variety of uncomfortable symptoms leading up to menstruation, and while some women manage these symptoms with medication, others look for natural alternatives due to medication side effects. Pomegranate is known for its rich antioxidant content and estrogen-like properties, which may help balance hormones and reduce the severity of PMS symptoms. By understanding how pomegranate can ease these symptoms, this study aims to offer a natural, potentially safer alternative to traditional medications. Participants in this study will take pomegranate supplements over an eight-week period. Researchers will monitor the severity of their PMS symptoms to see if there is any improvement. The study does not involve any invasive procedures, as pomegranate supplements are taken orally like regular vitamins. The goal is to evaluate whether the natural properties of pomegranate can effectively lessen the discomfort and distress caused by PMS, offering a more natural approach to managing these symptoms.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.60 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Supportive Care Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Female
Biological sex of participants that are eligible to enroll.From 18 to 49 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Inclusion Criteria: Women who experience PMS complaints (those with a PMSS total score of more than 50%) and who volunteer to participate in the research will be included in our study. Exclusion Criteria: * History of acute or chronic illness or history of medication and supplement use * PMSS total score \<50% * Irregular menstrual cycle * History of allergy to herbal medicine * Experiencing any stressful event during the intervention
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.One single intervention group is designated in this study
This study does not include a placebo group
Treatment Groups
Group I
ExperimentalStudy Objectives
Primary Objectives
Secondary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location