Comparision of the Clinical Efficacy of Different Desensitizing Toothpastes
Sodium Monofluorophosphate
+ Stannous Fluoride
+ Nano-Hydroxyapatite
Dentin Sensitivity
+ Stomatognathic Diseases
+ Tooth Diseases
Treatment Study
Summary
Study start date: May 1, 2022
Actual date on which the first participant was enrolled.Dentin hypersensitivity is a condition where the teeth become sensitive to hot or cold stimuli, affecting many people and leading to discomfort and potential dental issues over time. This study focuses on finding out how effective different types of desensitizing toothpastes are in reducing this sensitivity. The study targets adults who have at least two teeth experiencing this sensitivity. By comparing various toothpastes, such as those containing sodium fluoride, stannous fluoride, nano-hydroxyapatite, and a combination of arginine and calcium carbonate, the study aims to identify which toothpaste might provide the best relief. Understanding the effectiveness of these products can help improve daily life for those affected by dentin hypersensitivity and reduce the risk of related dental problems. Participants in the study are divided into four groups, each using a different type of toothpaste for a period of 16 weeks. The toothpastes are applied as part of their regular oral hygiene routine. The study evaluates the level of dentin hypersensitivity at the start, and then at the 2nd, 4th, and 16th weeks using specific scoring methods like VAS and Shiff scores, along with checking periodontal health. There are no specific risks noted, but the study's benefits could include finding a more effective way to manage tooth sensitivity, improving comfort and dental health in the long term.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.48 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.From 18 to 65 Years
Range of ages for which participants are eligible to join.Healthy volunteers allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Inclusion Criteria: * Dentin hypersensitivity complaints * Systemically healthy * Not during pregnancy \& lactation * No sensitivity treatment in the last 6 months * Forty-eight patients with positive response to VAS and Schiff tests were included. Exclusion Criteria: People who have; * Any systemic disease * Take regular medication for any other reason * Undergone periodontal surgery within the last 6 months, * History of allergy to toothpaste materials, * Active caries, restoration and/or bridge on the sensitive tooth, * Orthodontic appliances,
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.4 intervention groups are designated in this study
This study does not include a placebo group
Treatment Groups
Group I
Active ComparatorGroup II
Active ComparatorGroup III
Active ComparatorGroup IV
Active ComparatorStudy Objectives
Primary Objectives
Secondary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location