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The Metabolic Effects of Ginseng Oligopeptide Preparation on Non- Alcoholic Fatty Liver Disease With Obesity: a Randomized Controlled Double-blind Trial

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What is being tested

Ginseng oligopeptide (Ginseng extract)

+ Maltodextrin

Other
Who is being recruted

Digestive System Diseases+1

+ Fatty Liver

+ Liver Diseases

From 18 to 65 Years
+13 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Placebo-Controlled
Interventional
Study Start: December 2023
See protocol details

Summary

Principal SponsorPeking Union Medical College Hospital
Study ContactWei Chen, Doctor
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: December 25, 2023

Actual date on which the first participant was enrolled.

This study focuses on understanding how ginseng oligopeptide might help people suffering from non-alcoholic fatty liver disease who are also dealing with obesity. The main goal is to see if this natural compound can be an effective way to prevent and treat this liver condition. Non-alcoholic fatty liver disease is a common issue, especially among those with obesity, and finding new, effective ways to manage it is important for improving the health and quality of life for many people. Participants in this study are divided into two groups. One group receives the ginseng oligopeptide by mouth, while the other group receives a placebo, which is a harmless pill with no active ingredients. Researchers are measuring several health indicators, such as liver function, blood lipid levels, and blood glucose, as well as conducting liver ultrasounds to observe any changes. This helps determine how effective the ginseng oligopeptide is at improving liver health and managing the disease. The study aims to provide insights into how this treatment might benefit individuals with this condition.

Official TitleThe Metabolic Effects of Ginseng Oligopeptide Preparation on Non- Alcoholic Fatty Liver Disease With Obesity: a Randomized Controlled Double-blind Trial
NCT06167902
Principal SponsorPeking Union Medical College Hospital
Study ContactWei Chen, Doctor
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

200 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 65 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Digestive System DiseasesFatty LiverLiver DiseasesNon-alcoholic Fatty Liver Disease

Criteria

5 inclusion criteria required to participate
Meet the diagnostic criteria for non-alcoholic fatty liver disease ;

Aged 18-65 years old;

ALT, AST, GGT≤2×Upper Limit Of Normal(ULN);

BMI≥28Kg/㎡;

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8 exclusion criteria prevent from participating
Under 18 years old and over 65 years old;

Allergic to the ingredients of ginseng oligopeptide preparation;

Serum ALT, AST, GGT>2ULN;

Currently taking oral hepatoprotective drugs such as reduced glutathione, polyene phosphatidylcholine, and silibinin, etc.;

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Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

50% chance of being blinded to the placebo group

Treatment Groups

Group I

Experimental

Group II

Placebo

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.
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SuspendedNo study centers